Pancreatic cancer detection with magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography: a prospective controlled study

Adamek, Henning E.; Albért, J; Breer, H; Weitz, M.; Schilling, Dieter; Riemann, J. F.

doi:10.1016/s0140-6736(00)02479-x

Cited by 256 publications

(100 citation statements)

References 24 publications

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“…8). MRI has been reported to have a sensitivity of 84% and a specificity of 97% for detection of pancreatic tumors [26]. In a study comparing MRI with MR angiography to CT with CT angiography, there was no statistical difference in detection of vascular involvement greater than 180°and change in vascular contour [27].…”

Section: Ctmentioning

confidence: 96%

Imaging in Staging and Management of Pancreatic Ductal Adenocarcinoma

Vikram

Balachandran

2010

Indian J Surg Oncol

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Pancreatic cancer is a relatively common malignancy of the gastrointestinal tract for which complete surgical excision remains the only curative option. Being infiltrative in nature and bearing a complex anatomical relationship with various organs, peritoneal ligaments and vascular structures, accurate anatomical staging is key in treatment of these patients. In this article, we will discuss and provide a brief overview of anatomy and use of imaging in staging pancreatic cancer.

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Section: Ctmentioning

confidence: 96%

Imaging in Staging and Management of Pancreatic Ductal Adenocarcinoma

Vikram

Balachandran

2010

Indian J Surg Oncol

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“…ERCP may demonstrate smooth strictures, dilated common bile duct and proximal pancreatic duct. The demonstration of a smooth stenosis of the biliary tree is more suggestive of an EMP than adenocarcinoma where irregular stenosis is classical [37,41,65].…”

Section: Endoscopic Retrograde Cholangiopancreatographymentioning

confidence: 98%

Pancreatic Involvement by Plasma Cell Neoplasms

Silva

2011

J Gastrointest Canc

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Introduction Pancreatic involvement by plasma cell neoplasms is an extremely rare event, with only 50 cases described in the literature. They can present as a primary solitary extramedullary plasmacytoma or plasmacytoma secondary to a plasma cell myeloma. Clinical manifestations are due to the presence of a pancreatic mass usually in the pancreas head, which causes extra-biliary obstruction and abdominal pain. Methods Abdominal imaging including CT scan or endoscopic ultrasound with fine-needle aspiration tissue sampling is essential for the initial diagnostic procedure. However, immunohistochemical analysis of the biopsy specimen or flow cytometry of the aspirated material is crucial to prove the monoclonality and the final diagnosis of a plasma cell neoplasm. Discussion Management of these situations include radiotherapy, chemotherapy, surgery or combined therapy. Novel medications including the immunomodulatory drugs or the proteasome inhibitors followed by consolidation with intensive chemotherapy and haematopoietic stem cell transplantation are nowadays used as upfront treatment in the cases associated to a plasma cell myeloma. Conclusion Despite the rarity, plasma cell neoplasms should be considered in the differential diagnosis of obstructive jaundice and pancreatic neoplasms since they are potentially treatable situations.

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“…For pancreatic cancer, current existing molecular imaging techniques include positron emission tomography (PET) [5][6][7][8], single-photon emission computed tomography (SPECT) [9,10], MRI with contrast agent enhancement (such as magnetic nanoparticles) [11][12][13][14][15], optical/fluorescence imaging [14,16,17], and photoacoustic imaging (PAI) [18][19][20]. PET and SPECT involve ionization radiation with the long half-life of radiotracers which limits the temporal resolution.…”

Section: Introductionmentioning

confidence: 99%

Targeted Molecular Imaging of Pancreatic Cancer with a Miniature Endoscope

et al. 2017

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It is highly desirable to develop novel approaches to improve patient survival rate of pancreatic cancer through early detection. Here, we present such an approach based on photoacoustic and fluorescence molecular imaging of pancreatic tumor using a miniature multimodal endoscope in combination with targeted multifunctional iron oxide nanoparticles (IONPs). A novel fan-shaped scanning mechanism was developed to minimize the invasiveness for endoscopic imaging of pancreatic tumors. The results show that the enhancements in photoacoustic and fluorescence signals using amino-terminal fragment (ATF) targeted IONPs were~four to six times higher compared to that using non-targeted IONPs. Our study indicates the potential of the combination of the multimodal photoacoustic-fluorescence endoscopy and targeted multifunctional nanoparticles as an efficient tool to provide improved specificity and sensitivity for pancreatic cancer detection.

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Pancreatic cancer detection with magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography: a prospective controlled study

Cited by 256 publications

References 24 publications

Imaging in Staging and Management of Pancreatic Ductal Adenocarcinoma

Imaging in Staging and Management of Pancreatic Ductal Adenocarcinoma

Pancreatic Involvement by Plasma Cell Neoplasms

Targeted Molecular Imaging of Pancreatic Cancer with a Miniature Endoscope

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