Pancreatic abscess due to <i>Salmonella typhi</i>

Garg, Pradeep; Parashar, Sunil

doi:10.1136/pgmj.68.798.294

Cited by 16 publications

(8 citation statements)

References 4 publications

(1 reference statement)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Only a small number of heart or heart valve [53,75,115,129], pancreatic [33,45], or seminal vesicle abscesses [68] were reported. The patients with heart or heart valve infections typically had concomitant endocarditis, and the usual diagnostic modality was echocardiography.…”

Section: Discussionmentioning

confidence: 99%

Outcome of Medical Treatment of Bacterial Abscesses Without Therapeutic Drainage: Review of Cases Reported in the Literature

Bamberger

1996

Clinical Infectious Diseases

View full text Add to dashboard Cite

The usual treatment of bacterial abscesses, except lung or tubo-ovarian abscesses, includes therapeutic drainage. Increasing evidence suggests that some abscesses respond to antimicrobial therapy without drainage. To study this issue, a MEDLINE search of the literature was performed for cases of bacterial abscess in which treatment without definitive drainage was attempted. Four hundred sixty-five cases were identified. The most commonly involved organs were the liver, brain, and kidney. The success rate of antimicrobial therapy was 85.9%. Factors that predicted a less favorable outcome were abscess diameter of~5 em (odds ratio [OR] = 37.7; P = .0003), involvement of~1 organism (OR = 5.2; P = .014), presence of gram-negative bacilli (OR = 3.4; P = .022), length of therapy of <4 weeks (OR = 49.1; P < .0001), and use of an aminoglycoside as the only active agent (OR = 11.8; P = .008). Many bacterial abscesses can be treated without drainage; abscess size, the organisms involved, and therapy utilized may influence outcome.Bacterial abscesses usually require drainage for cure. Reasons postulated for the ineffectiveness of antibiotics in the treatment of abscesses include the presence of stationary-phase organisms, low pH, high protein content, the large number of bacteria within abscesses, ionic composition, low oxygen tension, sequestration of bacteria within leukocytes, low abscess zinc concentrations, and the presence of antimicrobial agent-deactivating enzymes [1]. Antimicrobial therapy is generally ineffective in experimental models of suppurative infections when initiation of therapy is delayed for ;?:24 hours [2].See the editorial response by Lerner on pages 604-7.It has long been recognized that lung abscesses respond to prolonged courses of antimicrobials without formal surgical drainage. Since many lung abscesses have air-fluid levels that were observed radiographically, suggesting bronchial communication, it is likely that lung abscesses spontaneously drain via the bronchial tree. It has also been well recognized that most abscesses of the tubo-ovarian region-especially those <8 em in diameter-respond to antimicrobial therapy without the need for surgical drainage [3], perhaps again because spontaneous drainage occurs via the fallopian tubes. Since the 1970s there has been an increasing number of reports of other abscesses, especially those involving the brain, liver, and kidney, that have responded to antimicrobial therapy without the need for a drainage procedure. This report reviews the literature regarding medical treatment ofbacterial abscesses in order to determine the extent of the clinical experience documented to date and to define the clinical, microbiological, and therapeutic features of abscesses responding to medical therapy. Since routine initial therapy for lung and tubo-ovarian abscesses no longer includes a drainage procedure, these cases were excluded. MethodsA MEDLINE search of the literature from 1966 to August 1994 was done to find all English-language reports of bacterial abscesses ...

show abstract

Section: Discussionmentioning

confidence: 99%

Outcome of Medical Treatment of Bacterial Abscesses Without Therapeutic Drainage: Review of Cases Reported in the Literature

Bamberger

1996

Clinical Infectious Diseases

View full text Add to dashboard Cite

show abstract

“…However, localized infection in the course of salmonellosis as acute pancreatitis is very rare. 5 There may be several factors for the presentation of S. sp. infection with the clinical picture of pancreatitis.…”

Section: Discussionmentioning

confidence: 99%

“…infections. 5 There are limited data on the frequency of infections leading to pancreatitis. 6 Cases of pancreatitis have been reported during the course of infections caused by agents including mumps virus, echovirus, enterovirus, Epstein-Barr virus, influenza virus, Escherichia coli, and Mycoplasma pneumoniae.…”

Section: Introductionmentioning

confidence: 99%

A Rare Complication during Salmonella sp. Infection in a 4-Year-Old Child: Acute Pancreatitis

Kılıç

Akın

Yazar

et al. 2020

Journal of Pediatric Infectious Diseases

View full text Add to dashboard Cite

Objective We aimed to report a rare complication of acute pancreatitis which developed during Salmonella infection. Methods We report a 4-year-old girl with pancreatitis that occurred after salmonella gastroenteritis. Discussion Salmonella sp. infections cause serious mortality and morbidity worldwide. Salmonella transmission is mostly fecal oral from contaminated water and foods. Acute pancreatitis expresses the acute inflammatory process of the pancreas. Inflammation of the pancreas associated with bacterial, viral, and fungal agents can lead to acute pancreatitis. There are limited data regarding the frequency of infections leading to pancreatitis. Here, a pediatric case with pancreatitis that occurred after salmonella gastroenteritis is reported. Conclusion Acute pancreatitis due to S. sp. infection is very rare in children. Pancreatitis should be considered in patients with gastroenteritis with typical abdominal pain.

show abstract

“…Mycobacterium tuberculosis, Klebsiella pneumoniae, Salmonella typhi and Corynebacterium coyleae infections have been reported too. [15][16][17][18][19][20] Extension of the abscess from nearby anatomic structures, hematogenous spread from a distant focus of infection, or lymphatic spread from the intestinal tract, are other possible causes for pancreatic abscesses having no history of acute pancreatitis. 14,21 Streptococcus anginosus group, as part of the normal gastrointestinal flora, it is rarely implicated in disseminated infections originating from colon diseases.…”

Section: Discussionmentioning

confidence: 99%

Unusual presentation of peripancreatic abscess associated with streptococcus anginosus and colonic diverticulosis

Berevoescu¹,

Bordea

Berevoescu

et al. 2019

Int Surg J

View full text Add to dashboard Cite

Pancreatic abscesses are rare and usually occur as a pancreatitis complication. The absence of acute pancreatitis and the clinical presentation that mimics a neoplasm are very unexpected. A 49-year-old man, known with arterial hypertension and chronic infection with virus hepatitis B came to the hospital for weight loss, marked asthenia, nausea/vomiting and jaundice, associated with mild pain in the upper abdomen. At admission, without fever and no medical history of acute pancreatitis. Laboratory values showed an important inflammatory syndrome, near normal pancreatic enzymes and increased tumour markers. Abdominal computed tomography (CT) revealed a heterogeneous fluid collection with gas bubbles inside, localized into the lesser sac that tended to extend peri splenic, towards the anterior and posterior pararenal spaces and the pelvis. Surgery has led to evacuation of peripancreatic and left retrocolic abscesses, associated with debridement and peritoneal drainage. The culture yielded Streptococcus Anginosus. At 7 days post-intervention hemoperitoneum occurred and was required a second intervention for haemostasis. Subsequent favourable clinical and biological evolution, with patient discharge from the clinic 16 days after admission. Repeated CT scans of the abdomen showed resolution of lesions and at colonoscopy it was observed uncomplicated colonic diverticulosis. In this case is highlighted a rare presentation of a peripancreatic pyogenic abscess caused by Streptococcus anginosus, associated with colonic diverticulosis.

show abstract

Pancreatic abscess due to Salmonella typhi

Abstract: Summary:Isolated involvement of the pancreas in Salmonella typhi bacteraemia is rare. A case of pancreatic abscess due to S. typhi is reported which was managed conservatively.

Cited by 16 publications

References 4 publications

Outcome of Medical Treatment of Bacterial Abscesses Without Therapeutic Drainage: Review of Cases Reported in the Literature

Outcome of Medical Treatment of Bacterial Abscesses Without Therapeutic Drainage: Review of Cases Reported in the Literature

A Rare Complication during Salmonella sp. Infection in a 4-Year-Old Child: Acute Pancreatitis

Unusual presentation of peripancreatic abscess associated with streptococcus anginosus and colonic diverticulosis

Contact Info

Product

Resources

About