In this article, we present our experience of trauma of the upper abdomen, mainly the duodenum and pancreas, and the challenges that we faced during pre-, intra-, and postoperative management of these patients. We also discuss the implementation of the techniques described in literature in the everyday practice. Four cases of trauma of the upper abdomen presented to our hospital and treated by our team are discussed. We present the technique implemented, the postoperative management, as well as dealing with complications. A brief review of literature is conducted to identify the best approach to diagnosis, imaging, and operating techniques. Abdominal blunt and penetrating injury poses a challenge to every trauma surgeon. These injuries are distinguished by their severity and unpredictability of intraoperative findings, as well as the difficulty of their management. The extent of the operation is dictated by the severity of the injury and the complexity of the technique should be proportionate to the experience of the surgeon. The most complicated cases might require additional techniques, procedures, or referral to a specialized center.