Pancreas divisum: Congenital anatomic variant or anomaly?

Delhaye, Myriam; Engelholm, L; Cremer, Michel

doi:10.1016/0016-5085(85)90193-3

Cited by 229 publications

(27 citation statements)

References 27 publications

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“…[1][2][3][4][5] The anomaly results from a failure of fusion of the dorsal and ventral pancreatic buds during fetal development. Several studies have shown an extremely high incidence of this anomaly, reaching 25%-50%, in patients with idiopathic pancreatitis.…”

Section: Introductionmentioning

confidence: 99%

A giant retention cyst of the pancreas (cystic dilatation of dorsal pancreatic duct) associated with pancreas divisum

Morise

Yamafuji

Tsuji

et al. 2002

Journal of Gastroenterology

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We describe a rare case of pancreas divisum associated with a giant retention cyst (cystic dilatation of the dorsal pancreatic duct), presumably formed following obstruction of the minor papilla. The patient was treated by pancreatico(cysto)jejunostomy. A 50-year-old man was admitted with complaints of increasing upper abdominal distension and body weight loss. There was no previous history of pancreatitis, gallstones, drinking, or abdominal injury. An elastic-hard tumor-like resistance was palpable in the upper abdomen. Computed tomography and ultrasound (US) examinations revealed a giant cystic lesion expanding from the pancreas head to the tail. Endoscopic retrograde cholangiopancreatography findings showed a looping pancreatic duct which drained only the head and uncinate process of the pancreas to the main papilla. A US-guided puncture to the cystic lesion revealed that the lesion continued to the main pancreatic duct in the tail of pancreas. The lesion was connected to a small cystic lesion, which was located inside the minor papilla, and ended there. The amylase level in liquid aspirated from the cyst was 37 869 IU/l, and the result of cytological examination of the liquid showed class II. A pancreatico(cysto)jejunostomy was performed, with the diagnosis being pancreas divisum associated with a retention cyst following obstruction of the minor papilla. The histological findings of a specimen from the cyst wall revealed that the wall was a pancreatic duct covered with mildly inflammatory duct epithelium; there was no evidence of neoplasm. The patient is currently well, and a CT examination 2 years after the operation showed disappearance of the cyst and normal appearance of the whole pancreas.

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Section: Introductionmentioning

confidence: 99%

A giant retention cyst of the pancreas (cystic dilatation of dorsal pancreatic duct) associated with pancreas divisum

Morise

Yamafuji

Tsuji

et al. 2002

Journal of Gastroenterology

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“…While the malformation is present in 5-15% of patients in autopsy series, only a few such patients develop recurrent pancreatitis [2,3]. Indeed, a recent large study failed to demonstrate a relationship between this anatomic variant and pancreatic disease [4]. Still, patients with pancreas divisum remain susceptible to other established causes of pancreatitis, and the influence of the congenital anomaly on the course of these illnesses is…”

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confidence: 96%

Traumatic pancreatitis in a patient with pancreas divisum: Clinical and radiographic features

et al. 1994

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A previously healthy patient with chronic hyperamylasemia and epigastric pain following blunt abdominal trauma complicated by retroperitoneal hematoma is reported. Endoscopic retrograde cholangiopancreatographic and computerized tomographic examinations revealed pancreatographic characteristics of pancreas divisum with traumatic disruption of the duct of Santorini and adjacent pseudocyst formation. Distal pancreatectomy with cystjejunostomy resulted in total recovery. This represents the first documented case of traumatic pancreatitis in a patient with pancreas divisum.

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“…It is an embryologic anomaly, occurring in the eighth week of fetal development, and resulting in non-union of the ventral and dorsal buds. Calculated from autopsy series 4 to 14 per cent (2,3,7,16) of the general population have PD and the corresponding figures from endoscopic retrograde pancreatography (ERP) studies are 1 to 7 per cent (5,6,8). Patients with PD are considered to run a risk of developing pancreatic pain and pancreatitis in the dorsal anlage due to relative outlet obstruction at the minor papilla (5,9,11,15,19,20,23,27).…”

mentioning

confidence: 99%

Computed Tomography Findings in Pancreas Divisum

Lindström¹,

Ihse²

1989

Acta Radiol

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In 29 patients with abdominal pain the diagnosis of pancreas divisum (PD) was verified by endoscopic retrograde pancreatography (ERP) via both the major and the minor papilla. Computed tomography (CT) was done in all patients to evaluate contour, volume, antero-posterior diameters and attenuation values of the gland in comparison with a normal reference series. Also, the validity of the CT grading of pancreatitis was assessed in comparison with ERP grading. Patients with PD had an increased cranio-caudal diameter of the pancreatic head (p

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Pancreas divisum: Congenital anatomic variant or anomaly?

Cited by 229 publications

References 27 publications

A giant retention cyst of the pancreas (cystic dilatation of dorsal pancreatic duct) associated with pancreas divisum

A giant retention cyst of the pancreas (cystic dilatation of dorsal pancreatic duct) associated with pancreas divisum

Traumatic pancreatitis in a patient with pancreas divisum: Clinical and radiographic features

Computed Tomography Findings in Pancreas Divisum

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