Pan-genome-scale metabolic modeling of
Bacillus subtilis
reveals functionally distinct groups
Maxwell Neal,
William Brakewood,
Michael Betenbaugh
et al.
Abstract:Bacillus subtilis
is an important industrial and environmental microorganism known to occupy many niches and produce many compounds of interest. Although it is one of the best-studied organisms, much of this focus including the reconstruction of genome-scale metabolic models has been placed on a few key laboratory strains. Here, we substantially expand these prior models to pan-genome-scale, representing 481 genomes of
B. subtilis
with 2,315 orthologous gene clusters, … Show more
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