Palmoplantar keratoderma unveiling renal cell carcinoma: A novel paraneoplastic presentation

Kamalakannan, K K; Arunprasath, P; Lanka, Padmavathy; Kothandapany, Srivenkateswaran

doi:10.4103/0378-6323.174410

Cited by 1 publication

(1 citation statement)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The sudden appearance of diffuse palmoplantar keratoderma, accompanied by itching in patients with RCC, which does not resolve with topical keratolytic agents and emollients, can be categorized as a paraneoplasia [92].…”

Section: Paraneoplastic Syndromes In Rccmentioning

confidence: 99%

The Cellular Stress and Cutaneous Manifestations in Renal Cell Carcinomas—A Narrative Review

Ene,

Nicolae,

Tampa

et al. 2024

JCM

View full text Add to dashboard Cite

The carcinomas originating from the renal cortex are the most aggressive renal malignancies, with a high tendency for metastasis. Understanding the incidence of cutaneous manifestations caused by renal carcinomas is a challenge. In the first part, this article summarizes a series of factors that promote oncogenesis, invasiveness, and the ability of renal cell carcinoma (RCC) to develop secondary cutaneous manifestations. It is postulated that the cellular stress response is one of the leading causes of developing dermatological events induced by cancers located at distant sites. Furthermore, the paper provides an overview of cutaneous complications associated with renal cancer, categorized as malignant manifestations (metastases, synchronous or metachronous cutaneous malignancies associated with renal cancer), non-malignant indirect cutaneous manifestations associated with renal cancer, and treatment consequences. The data presented in this article suggest that recognizing certain cutaneous disorders could assist the physician in the early identification of renal neoplasms and could lead to a better prognosis.

show abstract

Section: Paraneoplastic Syndromes In Rccmentioning

confidence: 99%