Palliative Cryotherapy in Inoperable Prostate Carcinoma

Sesia, G; Ferrando, U; Fontana, Gabriele; Laudi, M; Cauda, F

doi:10.1007/978-3-642-81095-4_9

Tumors of the Male Genital System

1977

DOI: 10.1007/978-3-642-81095-4_9

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Palliative Cryotherapy in Inoperable Prostate Carcinoma

G Sesia¹,

U Ferrando²,

Gabriele Fontana³

et al.

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Cryotherapy

Laudi

Fontana

2004

Urologia

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TRUS-guided transcutaneous cryotherapy in the treatment of the prostatic carcinoma is performed by perineal approach, the intraoperatory monitoring of temperatures and a mechanical hydraulic sonorguided separation between prostate and the anterior rectal wall. Six to eight probes are used, the Argon gas in the freezing phase (-10 °C and -40 °C) and Helio gas for heating phase. TRUS-guided cryoterapy is a possible therapeutich option in the treatment of localized or locally advanced prostatic carcinoma and after RT, in case of the relapse in alternative to the rescue prostatectomy. We examined in both procedures the most significant series concerning the oncologic results and morbility. At present, TRUS-guided cryotherapy represents a mininvasive therapeutic option in selected patients (ASA 2–3). For the future an evaluation of the survival years compared with quality of life and randomized studies will be necessary.

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Cryotherapy

Laudi

Fontana

2004

Urologia

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Cryotherapy for prostate cancer

Bermejo¹,

Pisters²

2003

Expert Review of Anticancer Therapy

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Cryotherapy, or the use of freezing, is a long-established method of tumor cell destruction. Although in the past cryotherapy was widely used as a local treatment for prostate cancer, this technique was abandoned not due to lack of efficacy but because the complication rate was unacceptably high. However, there has been a re-emergence in the popularity of cryotherapy for the treatment of localized prostate cancer due to improvements in instrumentation, tumor localization and treatment delivery. Using transrectal ultrasound imaging, prostate cryotherapy is currently delivered with multiple probes via a percutaneous transperineal approach. The extent of freezing can be precisely controlled and monitored with thermocouples and tissue destruction is monitored with real-time visualization of the prostate and surrounding structures. The role of cryotherapy in localized prostate cancer is reviewed.

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Palliative Cryotherapy in Inoperable Prostate Carcinoma

Cited by 2 publications

References 2 publications

Cryotherapy

Cryotherapy

Cryotherapy for prostate cancer

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