Palliative combined cutting and high-pressure balloon valvuloplasty in six dogs with severe, symptomatic subaortic stenosis

Sykes, K.T.; Gordon, Sonya G.; Saunders, Ashley B.; Vitt, Jordan P; O'Brien, Mackenzie; Fries, Ryan

doi:10.1016/j.jvc.2020.08.004

Cited by 6 publications

(3 citation statements)

References 21 publications

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“…Combination cutting and high-pressure balloons have been used to reduce pressure gradients and palliate clinical signs in dogs with severe subaortic stenosis. 14 The procedure in this patient failed to improve the severe LVOTO caused by the myxoma. On gross examination, the mass was found to be extremely firm, which may have made it resistant to scoring with the atherotomes of the cutting balloon or more resistant to tearing in the face of a high-pressure balloon.…”

Section: Discussionmentioning

confidence: 79%

Subaortic Cavitated Myxoma Causing Severe Left Ventricular Outflow Tract Obstruction in a Young Dog

Stack

Fries

Samuelson

2021

CASE

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Section: Discussionmentioning

confidence: 79%

Subaortic Cavitated Myxoma Causing Severe Left Ventricular Outflow Tract Obstruction in a Young Dog

Stack

Fries

Samuelson

2021

CASE

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“…There are reports of cutting balloon valvuloplasty (CBV) combined with high pressure balloon valvuloplasty (HPBV) in the literature, though the long-term clinical benefit, if any, has yet to be determined [ 59 ]. Other studies cite the intervention as an option for palliative care [ 60 ]. In human patients, percutaneous balloon dilation has been reported occasionally, but results are variable and unreliable, and the procedure is therefore not recommended in these patients.…”

Section: Clinical Treatmentmentioning

confidence: 99%

Subvalvular Aortic Stenosis: Learning From Human and Canine Clinical Research

Crofton,

Kovacs,

Stern

2023

Cardiol Res

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Subvalvular aortic stenosis (SAS) is the most common congenital heart disease (CHD) in dogs and is also prevalent in human children. A fibrous ridge below the aortic valve narrows the left ventricular outflow tract (LVOT) and increases blood flow velocity, leading to devastating side effects in diseased patients. Due to the similarities in presentation, anatomy, pathophysiology, cardiac development, genomics, and environment between humans and dogs, canine SAS patients represent a critical translational model of human SAS. Potential adverse outcomes of SAS include arrhythmias, left-sided congestive heart failure, endocarditis, exercise intolerance, syncope, and sudden cardiac death. The greatest divergence between canine and human SAS clinical research has been the standard of care regarding treatment of these outcomes, with pharmacological intervention dominating best practices in veterinary medicine and surgical intervention comprising the standard practice for human SAS patients. Regardless of the species, the field has yet to identify a treatment option to prevent disease progression or permanently remove the fibrous ridge, but historical leaps in SAS research support a continued translational approach as the most promising method for achieving this goal.

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“…2007, Sykes et al . 2020). In general, procedural options include surgery with and without cardiopulmonary bypass or venous inflow occlusion, interventional catheter‐based therapies and hybrid procedures that combine the use of surgery, catheters and devices.…”

Section: Diagnosis and Treatment Optionsmentioning

confidence: 99%

Key considerations in the approach to congenital heart disease in dogs and cats

Saunders

2021

J of Small Animal Practice

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Congenital heart disease is an important subset of all cardiovascular disease in dogs and cats that is present at birth and most often detected in young animals but can be diagnosed in adulthood. The range of abnormalities that can occur during development of the heart is vast incorporating simple and complex defects, varying degrees of severity and clinical presentations that include heart failure and cyanosis. While some defects do not result in morbidity in an individual animal, others cause severe clinical signs and death at a young age. Advances in imaging and expanding treatment options offer increasingly more possibilities in the diagnosis and management of congenital heart disease which is the focus of this review. The objective is to provide a broad overview of current practice and highlight key aspects to guide practitioners in their approach to congenital heart disease diagnosis and knowledge of available treatment options.

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Palliative combined cutting and high-pressure balloon valvuloplasty in six dogs with severe, symptomatic subaortic stenosis

Cited by 6 publications

References 21 publications

Subaortic Cavitated Myxoma Causing Severe Left Ventricular Outflow Tract Obstruction in a Young Dog

Subaortic Cavitated Myxoma Causing Severe Left Ventricular Outflow Tract Obstruction in a Young Dog

Subvalvular Aortic Stenosis: Learning From Human and Canine Clinical Research

Key considerations in the approach to congenital heart disease in dogs and cats

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