Palladium Nanoparticles on Thermoresponsive Hydrogels and their Application as Recyclable Suzuki–Miyaura Coupling Reaction Catalysts in Water

Abstract

Palladium nanoparticles were immobilized on PNIPAM:4-VP hydrogels. The resultant püalladium catalysts showed high activities for Suzuki-Miyaura coupling reactions in water. The recyclability of the catalysts was improved by using 4-VP as a co-monomer in the hydrogels due to reduced Pd leaching during the reactions.

Novel palladium nanoparticles supported on β‐cyclodextrin@graphene oxide as magnetically recyclable catalyst for Suzuki–Miyaura cross‐coupling reaction with two different approaches in bio‐based solvents

“…Pd nanoparticles immobilized onto polymers have been extensively employed in various cross‐coupling reactions . Nonetheless, there are just a few reports of the utilization of magnetically separable nanoparticles stabilized by hydrophilic polymers for catalysed cross‐coupling reactions under eco‐friendly conditions …”

Azide–alkyne cycloaddition reactions in water via recyclable heterogeneous Cu catalysts: reverse phase silica gel and thermoresponsive hydrogels

“…Poly(N-isopropylacrylamideco-4-vinylpyridine) (pNIPAM-VP) hydrogels were prepared via free radical solution polymerization using N-isopropylacrylamide (NIPAM), N,N 0 -methylenebis-acrylamide (MBAAm), and 4-vinylpyridine (4-VP) according to a previously reported procedure. 55 As outlined in Scheme 2, copper coordination by [Cu(CH 3 CN) 4 ]PF 6 and CuSO 4 was followed. The morphology of the resulting catalysts Cu(I)@pNIPAM-VP and Cu(II)@pNIPAM-VP was determined via SEM imaging.…”

“…These properties make it possible to use water as a solvent for organic reactions. These solid supports were applied to the syntheses of Pd, Au immobilized heterogeneous catalysts and organic reactions such as hydrogenations, 53 Suzuki-Miyaura couplings, 54,55 Heck-Mizoroki couplings, 56 Sonogashira couplings, 56 Tsuji-Trost reactions, 57 and A-3 coupling reactions 58 that were performed in water. Herein, we wish to demonstrate that our supports can be extended to other metal catalyzed organic reaction applications.…”

Aziridine- and Azetidine-Pd Catalytic Combinations. Synthesis and Evaluation of the Ligand Ring Size Impact on Suzuki-Miyaura Reaction Issues

“…The biaryl motif can be found in numerous natural products, agrochemicals, drugs, polymers, ligands and thus triggered the attention of the scientific community for a wide range of applications [2][3][4][5][6][7][8][9]. If the formation of a biphenyl motif belongs nowadays to a textbook knowledge, the past decade has witnessed spectacular innovations and improvements such as ligandless transformations [10], supported or nanostructured catalytic systems [11][12][13], performing additives [14,15], neat and/or aqueous conditions [2,13,15], MW activations [10] for example.…”