Palladium‐Catalyzed Synthesis of Carboxylic Acid Anhydrides from Alkenes via in situ Generated Carboxylic Acids
Ashok Ramakrishnan,
Elisabeth Bouwman
Abstract:We herein present a carbonylative strategy to synthesize acid anhydrides from alkenes via in situ generated carboxylic acids. Formic acid (FA) reacts with alkene and CO under catalytic conditions to generate carboxylic acids. With our established palladium‐based catalytic reaction conditions and modulating the alkene:formic acid ratio to at least 2:1, symmetric acid anhydrides were effectively generated. The catalytic process was applied to various alkenes, simple as well as with various functional groups, to … Show more
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