Palladium‐Catalyzed Regioselective C‐H Bond ortho‐Acetylation and Oxidative Homocoupling of N‐Arylcarbamates

Abstract

An efficient and straightforward protocol for the regioselective acyloxylation of N-arylarbamates via Pd-catalyzed CÀ H bond functionalization has been demonstrated. The aliphatic and benzoic acid derivatives were used as the acyloxyl source to convert aromatic sp 2 CÀ H bonds into CÀ O bonds. Additionally, the oxidative homocoupling of N-arylarbamates were evaluated and gave the corresponding homocoupled products in good yields.

Palladium‐Catalyzed Direct ortho‐C–H Bond Sulfonylation and Halogenation of Phthalazine‐1,4‐diones

“…To continue our research interest aiming at N ‐heterocycle directed C–H bond functionalization of arenes, herein, we report the first Pd‐catalyzed C–H activation/sulfonylation and halogenation reactions of phthalazindiones. These approaches afford predominantly mono ‐functionalized products under mild and oxidant‐free reaction conditions using a palladium catalytic system and readily accessible and inexpensive reagents as functional group sources (Scheme h).…”