Palladium‐Catalyzed Cross‐Coupling Reactions and Electrocyclizations—Efficient Combinations for New Cascade Reactions.

Abstract

ca. 30 refs.]. -(DE MEIJERE*, A.; SCHELPER, M.; KNOKE, M.; YUCEL, B.; SUENNEMANN, H. W.; SCHEURICH, R. P.; ARVE, L.; J.

Suzuki Reactions in Water Catalyzed by an Active and Reusable PMO‐Type Pd(II) Organometal Catalyst with Cage‐Like Mesoporous Structure

“…[1] Among them, Pd(II) organometalcatalyzed coupling reactions between arylboronic acids and aryl or alkenyl halides, known as the Suzuki reaction, are of fundamental significance in constructing C -C bonds [2][3][4] and also of great industrial importance in producing fine chemicals, agrochemicals, pharmaceutical intermediates, and precursors of natural products. [5][6][7] Recently, they are also used as homogeneous catalysts with high activity and selectivity in water-medium organic reactions, which could be regarded as one important branches of green chemistry since the replacement of volatile organic solvents by water could greatly reduce the environmental pollution. [8][9][10][11][12] However, such homogeneous catalyst is difficult to be separated from the reaction system, which limits its recycle and reuse, leading to the high cost and even the environmental pollution from heavy metallic ions.…”