Abstract:Palladium‐catalyzed Suzuki–Miyaura (SM) coupling is a valuable method for forming C─C bonds, including those between aryl moieties. However, achieving atroposelective synthesis of axially chiral styrenes via SM coupling remains challenging. In this study, a palladium‐catalyzed atroposelective Suzuki–Miyaura coupling between gem‐diborylalkenes and aryl halides is presented. Using the monophosphine ligand Me‐BI‐DIME (L2), a range of axially chiral tetra‐substituted acyclic styrenes with high yields and excellent… Show more
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