Palladium-Catalyzed Annulations via Sequential C–H Activations of C(sp2)–H/C(sp3)–H or C(sp3)–H/C(sp3)–H Bonds
Wan-Xu Wei,
Mateusz Czajkowski,
Yangjin Kuang
et al.
Abstract:Palladium-catalyzed C−H annulation reactions represent a compelling strategy to construct complex ring systems with high step economy. While there are many approaches to annulate structures by activation of a single C−H bond, transformations that proceed by activation of multiple C−H bonds are less explored. This is especially true for examples where one of the reacting C−H bonds is located at an sp 3 center. However, exciting developments in palladium-catalyzed C−H activation continue to expand the scope of t… Show more
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