Palladium/Carbon Catalyzed Hydrogen Transfer Reactions using Magnesium/Water as Hydrogen Donor

Abstract

A new methodology is developed for the hydrogenation reaction using magnesium/water system, as hydrogen source under catalytic palladium on activated carbon (Pd/C). The method is highly efficient for the chemoselective reduction of wide range of unsaturated aldehydes and ketones. The process is also found to be suitable when we think about green chemistry for the ecofriendly hydro-dehalogenation of aromatics. From practical point of view this new methodology is the most attractive, efficient, economical and convenient approach towards industrially important reduction transformations. This report is intended to highlight the use of Mg/H 2 O system in these organic transformations which can be easily adopted in industrial scale for the bulk production of hydrogenation products.

Two-step hydrogen transfer catalysis conversion of lignin to valuable small molecular compounds

“…Like the Raney Ni catalyst, Pd/C catalyst plays an important role in industrial applications such as pharmaceutical production [18,19]. It can be also used as a catalyst for hydrogen transfer reaction.…”

Pd doped carbon nitride (Pd-g-C3N4): an efficient photocatalyst for hydrogenation via an Al–H2O system and an electrocatalyst towards overall water splitting

“…Eventually, Al foil as an active support donates the electrons to a H 2 O molecule to generate H 2 and gets converted into Al 2 O 3 simultaneously. 52 However, a big piece (5 cm 2 < 2 cm 2 < 1.5 cm 2 < 1 cm 2 ) of aluminum foil does not exhibit a complete hydrogenation process probably due to the lower surface area available for water to react (Fig. 4a).…”

Synthesis of deuterium‐labeled d3‐androstenone and d3‐skatole for boar taint analysis

“…Synthesis of [5,6,7‐ 2 H 3 ]‐5 α ‐androst‐16‐en‐3‐one ( 7 ) was achieved in a four‐step synthesis (Scheme ). The first step of the modified procedure was the modification of a palladium‐catalyzed hydrogenation . Deuteration of commercially available 3 β ‐hydroxy‐androst‐5‐en‐17‐one ( 3 ) was achieved by means of Pd/C in a magnesium/D 2 O/1,4‐dioxane system, which allowed for sufficient educt dissolution.…”