Palladium(0) complexes of (P,P) and (P,N) ligands immobilized on silica gel as catalysts in selective Heck type carbon–carbon coupling reactions

Deep Learning in Drug Discovery

“…Use of PN ligands immobilized on silica gel has also been reported; the authors claim 30 recycles with only 10–15% loss of activity when they applied their catalyst in the Heck reaction on activated iodo‐ and bromoarenes 73. However this constitutes a total TON of 15,000, which still compares poorly to Leadbeater’s results, who achieved a TON of 50,000 in a single run in a range of Heck reactions using low loadings of palladium acetate 56b.…”

Heterogeneous Pd catalysts supported on silica matrices

“…Similarly to MCM-41supported poly[(3-mercaptopropyl)siloxane palladium(0)] complex obtained earlier, this Pd catalyst deposited over phosphino-functionalised MCM-41 was an active and stereoselective catalyst for the Heck arylation of conjugated alkenes with bromoarenes. 109 Similar approach was employed by Singh et al 110 for immobilization of Pd(0) on silica gel. The prepared materials catalysed C-C coupling reactions of substituted aryl bromides and iodides with acrylic acid or styrene in yields up to 92%.…”

Solid phase extraction using silica gel modified with azo-dyes derivative for preconcentration and separation of Th(IV) ions from aqueous solutions

“…One approach increasingly researched in preparing novel materials as support media in solid/liquid separations is the use of silica gel with organic functionalities which are further chemical modified. [40][41][42]. Large number of reactive cites in silica cells can be immobilized number of organic molecules to enhance their adsorptive metal uptake [43].…”