Palladium(0)‐Catalyzed Suzuki—Miyaura Cross‐Coupling Reactions of Potassium Aryl‐ and Heteroaryltrifluoroborates with Alkenyl Bromides.

Abstract

Alkenes Q 0083Palladium (0)-Catalyzed Suzuki-Miyaura Cross-Coupling Reactions of Potassium Aryl-and Heteroaryltrifluoroborates with Alkenyl Bromides. -The process offers an efficient and stereospecific route to styrene derivatives and other unsaturated arenes and a number of functional groups is tolerated. -(MOLANDER*, G. A.; FUMAGALLI, T.; J. Org. Chem. 71 (2006) 15, 5743-5747; Dep. Chem., Univ. Pa., Philadelphia, PA 19104, USA; Eng.) -Jannicke 48-073

Direct stereoselective α-arylation of unmodified enals using an organocatalytic cross-coupling-like reaction

“…State-of-the-art approaches to these targets use Pd(0)-catalysed cross-coupling protocols, including Suzuki -Miyaura reaction of potassium aryl trifl uoroborates with alkenyl bromides ( Fig. 1a ) 35 and the reaction of benzyl bromides with diazoesters ( Fig. 1b ) 36 .…”