Paliperidone-Related Peripheral Edema

Self-limiting Atypical Antipsychotics-induced Edema: Clinical Cases and Systematic Review

“…In this review of cases, risperidone, olanzapine, and quetiapine were reported at the same rate of 29.4%. In a review by Chen et al .,[ 13 ] risperidone and olanzapine were the drugs most likely to be associated with edema and followed by quetiapine.…”

“…[ 5 6 7 ] Among atypical antipsychotics, edema has been reported in individuals using risperidone,[ 8 ] quetiapine,[ 9 ] ziprasidone,[ 10 ] amisulpride,[ 11 ] clozapine,[ 12 ] and paliperidone. [ 13 ]…”

Bilateral Pretibial Edema Associated with Paliperidone Palmitate Long-acting Injectable: A Case Report

“…Chen et al 12). described the development of edema in the dorsal side of the patient’s feet 2 weeks after the initiation of treatment with 9 mg paliperidone, which disappeared completely after the discontinuation of paliperidone.…”

“…Chen et al 12). reported that paliperidone and risperidone share common pathogenic pathways that may induce edema.…”

“…Although there is only one published case report of peripheral edema related to paliperidone, to our knowledge, there is no case report in the published literature on peripheral edema associated with paliperidone palmitate LAI 12). Herein, we present the case of a patient who developed pretibial edema after paliperidone palmitate LAI treatment.…”