Palatine tonsils in smoker and non‐smoker patients: a pilot clinicopathological and ultrastructural study

Torre, Valerio; Bucolo, Sebastiano; Giordano, Carlo; Cicciarello, Rocco; Cavallari, Vittorio; Garofalo, L.; Beatrice, Fabio

doi:10.1111/j.1600-0714.2005.00319.x

Cited by 16 publications

(10 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…No patient of our patient population had presented with a bilateral PTA, while others reported rates ranging between 0.8 and 4.9 % [27,30,[32][33][34]. In accordance with most studies [6,[35][36][37][38][39][40][41][42][43] smoking habits were overrepresented (43.8 %) in our patient population. In contrast to other studies, none of our patients had presented with a concomitant infectious mononucleosis [11,[44][45][46] or Kawasaki's disease [37,[44][45][46][47][48][49][50][51][52].…”

Section: Discussionsupporting

confidence: 93%

Cranial tonsillotomy for peritonsillar abscess: what a relief!

Windfuhr

Nematian

Ziogou

2016

Eur Arch Otorhinolaryngol

View full text Add to dashboard Cite

Peritonsillar abscess (PTA) is a common infection of the oropharynx resulting in painful swallowing, sometimes associated with fever, trismus and a typical voice alteration. Several draining methods have been suggested, including needle aspiration (NA), incision and drainage (ID), or abscesstonsillectomy. However, a gold standard of surgical therapy still does not exist. The aim of this study was to evaluate the outcome in patients who had undergone ID supplemented by cranial tonsillotomy (IDTT) as first-line treatment. A retrospective chart review of all patients who had undergone IDTT at our department in 2015 was performed. Demographic data, clinical findings, pain intensity on a 10-point visual analog scale, operation time and routine bloods before and after IDTT were collected. In addition, a 10-point visual analog scale (VAS) was utilized to measure personal satisfaction 2 weeks and 2 months after surgery. A total of 104 procedures were performed in 65 male and 38 female patients (median age 35 years), including one patient with a contralateral PTA 2 weeks after IDTT. Three patients had experienced abscess formation after admittance for antibiotic treatment of acute tonsillitis. 57.7 % of all patients denied intake of antibiotic therapy in their history at initial presentation. Patients were hospitalized for 3 days (median). The median pain intensity (VAS) within the first three postoperative days was 2, 1 and 1, respectively. Two weeks and 2 months after surgery patients were highly satisfied with the procedure (median value 10). Bleeding complications did not occur. IDTT is a novel surgical concept and associated with great patient comfort. It is safe, easy to learn and associated with an early return to normal diet and physical activity. These findings are supported by a rapid normalization of white blood cell count and C-reactive protein. IDTT eliminates the necessity of painful re-draining of the wound cavity and is free of bleeding complications. In contrast to ID and NA, histological examination of tonsillar tissue is feasible to disclose a previously undetected malign disease. Further analysis is warranted to verify the success rate in the long-term.

show abstract

Section: Discussionsupporting

confidence: 93%

Cranial tonsillotomy for peritonsillar abscess: what a relief!

Windfuhr

Nematian

Ziogou

2016

Eur Arch Otorhinolaryngol

View full text Add to dashboard Cite

show abstract

“…Smokers and non-smokers with chronic tonsillitis were compared and a longer history of recurrent tonsillitis and marked morphological changes were identified in smokers. [17] In our study, sore throat due to tonsillitis and pharyngitis was found to be lower in ex-smokers, whereas there was no difference in smokers.…”

Section: Discussioncontrasting

confidence: 43%

Relationship between smoking and otorhinolaryngological symptoms

Şanli¹

2016

Kulak Burun Bogaz Ihtis Derg

View full text Add to dashboard Cite

show abstract

“…Histopathologically, smoking causes cellular and structural alterations in tonsils, leading to an increased oral acquisition of HPV [36]. This has been corroborated clinically as researchers have observed a high prevalence of HPV infection in smokers, particularly current smokers [37].…”

Section: Discussionmentioning

confidence: 97%

Human papillomavirus, smoking, and head and neck cancer

Sinha

Logan

Mendenhall

2012

American Journal of Otolaryngology

View full text Add to dashboard Cite

Aims Smoking and human papillomavirus (HPV) are both distinct risk factors for head and neck cancer but the nature of interaction between these two risk factors in development of head and neck cancer remains unclear The purpose of this review is to determine the potential effect of smoking in causation of HPV related head and neck carcinoma. Method A literature search was carried out using keywords human papillomavirus, head and neck cancer, smoking, tobacco, and cervical cancer. The English language articles, references and other relevant studies evaluating the association of smoking, HPV and risk of head and neck cancer were collected and analyzed. Conclusion Overall, our review points to smoking tobacco posing an additional risk for development of head and neck cancer in the presence of HPV infection. This is consistent with available laboratory data which show evidence of biological plausibility for interaction between smoking and progression of HPV infection to carcinogenesis. It is therefore important that cessation of smoking is promoted in smokers with HPV infection.

show abstract

Palatine tonsils in smoker and non‐smoker patients: a pilot clinicopathological and ultrastructural study

Abstract: These preliminary results suggest a possible interference of cigarette smoking with the therapy response as well as a possible role of tobacco smoke in impairment of inflammatory response. Results are critically analysed and discussed. Literature data on this subject are reviewed.

Cited by 16 publications

References 24 publications

Cranial tonsillotomy for peritonsillar abscess: what a relief!

Cranial tonsillotomy for peritonsillar abscess: what a relief!

Relationship between smoking and otorhinolaryngological symptoms

Human papillomavirus, smoking, and head and neck cancer

Contact Info

Product

Resources

About