Palatal presentation of scleroma

Bhargava, Deepa; Date, Anand

doi:10.1258/0022215011908621

Cited by 11 publications

(5 citation statements)

References 4 publications

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“…In this study, we used Rifampicin as a drug of treatment; only 25% of the cases were cured histopathologically, and that coincides with Bhargava and Date 65 , who reported no response to Rifampicin 450 mg daily for four months. However, in clinical assessment follow up nasal obstruction decreased by 55% of cases, and nasal crustation decreased by 40% of cases another regimen of 6months of treatment was continued for those who experienced clinical improvement despite positive biopsy.…”

Section: Medical Treatmentsupporting

confidence: 70%

Safety and Efficacy of Rifampicin in treatment of Rhinoscleroma, Single Institutional Experience on patients over two years period

Bakhiet

Hakeem

Saleh

et al. 2021

Egyptian Journal of Neck Surgery and Otorhinolaryngology

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Introduction: Rhinoscleroma is a chronic granulomatous infectious disease of the upper respiratory tract. It affects the nose in the majority of patients, but the upper air passages, trachea, and bronchi may also be involved either with or without nasal granuloma. Objectives To evaluate the efficacy of Rifampicin 300 mg twice daily for six weeks in treating histologically active rhinoscleroma patients. Evaluation of the drawbacks and side effects of Rifampicin used in the treatment of rhinoscleroma. Patients and Methods: This prospective randomized descriptive clinical trial was conducted from January 2018 to December 2019 on 20 patients diagnosed clinically and histopathologically as rhinoscleroma scheduled for treatment and received the usual regimen given for free by the Ministry of Health in Egypt; Rifampicin 300 mg twice daily one hour before meals for six months. Results: The impact of medical treatment with Rifampicin on histopathological examination after treatment showing that only 25% of cases are cured. Conclusion: Rifampicin is a less effective and safe drug in the treatment of active rhinoscleroma. Clinical assessment and histopathological examination are nearly correlated and could be used as a parameter in follow-up and assessment.

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Section: Medical Treatmentsupporting

confidence: 70%

Safety and Efficacy of Rifampicin in treatment of Rhinoscleroma, Single Institutional Experience on patients over two years period

Bakhiet

Hakeem

Saleh

et al. 2021

Egyptian Journal of Neck Surgery and Otorhinolaryngology

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“…Involvement of the skin of the soft tissue of the face mainly the upper lip, nasal ala, cheeks, lacrimal passages and hard and soft palate have been managed either surgically or by chemotherapy . One case in our series presented with nasal deformity, complete stenosis of the nasal cavity and nasopharynx, upper lip ulceration, soft palate, uvula and tonsillar pillar fibrosis.…”

Section: Discussionmentioning

confidence: 91%

Airway scleromas and their extensions

Molumi

Dubey

2015

ANZ Journal of Surgery

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“…[5] Drugs of choice include quinolones, doxycycline or tetracycline and less frequently streptomycin and rifampicin. [12][13][14] Rifampicin provides good results in the treatment of rhinoscleroma, but requires effective monitoring of toxicity. [15] Because of high rate of relapses the long-term follow-up of the patient is necessary.…”

Section: Discussionmentioning

confidence: 99%

Rhinoscleroma With Laryngotracheal Involvement, Causing Diagnostic Dilemma

Patil¹,

Patil²,

Biswas³

et al. 2013

jemds

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Rhinoscleroma is a chronic, progressive, granulomatous disease caused by Klebsiella Rhinoscleromatis. It generally involves the nose but can affect other parts of the respiratory tract. It is uncommon but still evident in some parts of the world. We are reporting a case of a 25 year-old male who presented with nasal mass, dyspnoea and hoarseness of voice and created a diagnostic dilemma due to laryngeal involvement but histopathological examination revealed the diagnosis of rhinoscleroma. Apart from surgical debridement of the mass in nasal cavity, the patient was also treated with streptomycin, rifampicin and ciprofloxacin. He was asymptomatic in the follow-up. It is thus important to consider rhinoscleroma in cases of chronic nasal obstruction and histopathology plays a vital role in confirming the diagnosis.

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Palatal presentation of scleroma

Cited by 11 publications

References 4 publications

Safety and Efficacy of Rifampicin in treatment of Rhinoscleroma, Single Institutional Experience on patients over two years period

Safety and Efficacy of Rifampicin in treatment of Rhinoscleroma, Single Institutional Experience on patients over two years period

Airway scleromas and their extensions

Rhinoscleroma With Laryngotracheal Involvement, Causing Diagnostic Dilemma

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