Pakistan’s transgender health disparities—a threat to HPV elimination?

Awan, Usman Ayub; Khattak, Aamer Ali; Bai, Qian; Khan, Suliman

doi:10.1016/j.lansea.2024.100351

The Lancet Regional Health - Southeast Asia

2024

DOI: 10.1016/j.lansea.2024.100351

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Pakistan’s transgender health disparities—a threat to HPV elimination?

Usman Ayub Awan,

Aamer Ali Khattak,

Qian Bai

et al.

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HPV in Breast Carcinogenesis: Friend, Foe, or Fellow Traveler?

Ayub Awan,

Siddique

2024

New Findings on Human Papillomavirus [Working Title]

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Breast Cancer (BC) is a major public health problem and a leading cause of death and morbidity among women worldwide, with increasing incidence rates over the past decade. Several risk factors, such as reproductive history, lifestyle, and environmental exposure, have been associated with BC, but they only account for 20 to 50% of the cases. Viral infections, especially the Human papillomavirus (HPV), have been suggested as potential etiological agents of BC, but the causal link remains unclear. Herein, we review the prevalence of HPV in BC development and progression, focusing on the molecular mechanisms that HPV employs to infect and transform mammary epithelial cells. We also discuss the modes of transmission of HPV to the breast tissue, such as hematogenous or lymphatic spread, direct inoculation, or sexual contact, and the challenges and implications of HPV detection and prevention in BC. We highlight the possible interactions between HPV and other factors, such as genetic susceptibility and immune response, that may influence the outcome of HPV infection in BC. We provide some directions for future research and clinical practice in this field.

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HPV in Breast Carcinogenesis: Friend, Foe, or Fellow Traveler?

Ayub Awan,

Siddique

2024

New Findings on Human Papillomavirus [Working Title]

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

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Pakistan’s transgender health disparities—a threat to HPV elimination?

Cited by 1 publication

References 14 publications

HPV in Breast Carcinogenesis: Friend, Foe, or Fellow Traveler?

HPV in Breast Carcinogenesis: Friend, Foe, or Fellow Traveler?

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