While the majority of reported paired electrochemical reactions involve carefully matched cathodic and anodic reactions,t he precise matching of half reactions in an electrolysis cell is not generally necessary.D uring ac onstant current electrolysis almost any oxidation and reduction reaction can be paired, and in the presented work we capitalize on this observation by examining the coupling of anodic oxidation reactions with the production of hydrogen gas for use as ar eagent in remote,P d-catalyzed hydrogenation and hydrogenolysis reactions.T ot his end, an alcohol oxidation, an oxidative condensation, intramolecular anodic olefin coupling reactions,anamide oxidation, and amediated oxidation were all shown to be compatible with the generation and use of hydrogen gas at the cathode.T his pairing of an electrolysis reaction with the production of achemical reagent or substrate has the potential to greatly expand the use of more energy efficient paired electrochemical reactions.Paired electrochemical reactions that produce desirable products at both the anode and cathode are frequently put forth as am ethod for optimizing the energy efficiency of oxidation and reduction reactions, [1][2][3] and there are outstanding examples of their utility. [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] Fore xample,t he chloro-alkali process that generates sodium hydroxide (reduction of water at the cathode) and chlorine gas (oxidation of chloride at the anode) from sea water is currently conducted on amassive scale. [19] Many other efforts have been dedicated as well, particularly in the general area of energy conversion. [20][21][22][23][24][25][26][27][28][29] However,inspite of the potential paired electrochemical reactions hold for running more sustainable processes and the impressive examples illustrating this potential, the technique remains primarily of interest to chemists specifically engaged in the development of new electrochemical methods.A number of factors contribute to this situation. These factors range from little need to consider the energy efficiencyo f synthetic methods conducted in an academic laboratory setting to the impression that paired electrochemical reactions require "carefully matched" oxidation and reduction reactions and hence have limited synthetic generality.W ith respect to the first point, academic chemists are becoming increasingly aware of the need for more sustainable synthetic methods and strategies.I nt hat context, it makes sense to examine methods that meet the challenge from both ap erspective of atom and energy economy.P aired electrolysis reactions offer such an opportunity.T he second point raised above represents ap otentially more significant barrier. If paired electrochemical reactions really do require "carefully matched" oxidation and reduction reactions that limit the generality of the products that can be made,t hen interest in the reaction among the synthetic community will be equally limited. Fortunately,the perception that paired electrochemical reactions require...