Painful stimulation increases functional connectivity between supplementary motor area and thalamus in patients with small fibre neuropathy
Sebastian Scheliga,
Maike F. Dohrn,
Thilo Kellermann
et al.
Abstract:BackgroundThe lead symptom of small fibre neuropathy (SFN) is neuropathic pain. Recent functional magnetic resonance imaging (fMRI) studies have indicated central changes in SFN patients of different etiologies. However, less is known about brain functional connectivity during acute pain processing in idiopathic SFN.MethodsWe conducted fMRI with thermal heat pain application (left volar forearm) in 32 idiopathic SFN patients and 31 healthy controls. We performed functional connectivity analyses with right supp… Show more
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