Painful erythema of the scrotum

IgG4‐related disease manifesting as scrotal swelling

“…Correspondence Clinical Letter the scrotum, such as red scrotum syndrome, which usually manifests as sharply demarcated erythema of the scrotal skin with a burning sensation and pain [11,12].…”

Skrotalschwellung bei IgG4‐Autoimmunerkrankung

“…Der histologische Befund zeigt regressive Keimzentren ohne Infiltration eosinophiler Granulozyten [10]. Die Differentialdiagnose dieses Patienten umfasste auch einige im Skrotum vorkommende Hauterkrankungen, wie das Red-Scrotum-Syndrom, das meist als scharf begrenztes Erythem der Skrotalhaut mit brennendem Gefühl und Schmerzen auftritt [11,12].…”

Letter to the editor regarding Chen et al. “IgG4‐related disease manifesting as scrotal swelling” in J Dtsch Dermatol Ges 2021; 19(8): 1201–3

“…The scrotum painlessness and the failure of antibiotic therapy may contribute to the prolonged course of the disease in this article. Secondly, some of the differential diagnoses of scrotal swelling are described in detail, including sarcoidosis, lymphomas, multicentric Castleman disease, angiolymphoid hyperplasia with eosinophilia and red scrotal syndrome [3]. However, testicular tuberculosis, testicular tumors and hydrocele due to retroperitoneal fibrosis involving the ureter, inferior vena cava, and abdominal aorta and its branches appear to be more common etiologies of scrotal swelling in clinical practice [4].…”