Painful diabetic neuropathy

Abstract

Summary Chronic painful diabetic neuropathy causes symptoms that can last for many years and severely impair the quality of life of affected patients. This review describes the epidemiology, pathophysiology and treatment of chronic neuropathic pain. Particular emphasis is placed on a comprehensive review of the management of painful symptoms through a detailed review of the published literature using a variety of databases particularly Medline and EMBASE.

Sleep Impairment in Patients With Painful Diabetic Peripheral Neuropathy

“…2,3,19 Patients with painful DPN experience nocturnal exacerbations of neuropathic pain symptoms, including hyperesthesia and allodynia, and even contact with bedclothes can cause severe pain sensation and disturb sleep. 3,8,20,21 However, no studies have documented the full spectrum of sleep problems associated with painful DPN.…”

Implementierung eines standardisierten perioperativen Schmerzmanagementkonzepts in drei Krankenhäusern eines Klinikverbundes

“…Epidurale Anäs-thesieverfahren vermindern die pulmonale Morbidität [1,11] und setzen das Risiko einer tiefen Beinvenenthrombose und Lungenembolie herab [24], fördern den physiologischen Schlaf und Appetit [2], reduzieren die Krankenhausaufenthaltsdauer [33] und senken die Krankenhauskosten [17]. Brodner et al [5] zeigten eine reduzierte Liegedauer auf der Intensivstation und eine reduzierte Reintubationsrate.…”

Pain in diabetic neuropathy case study: whole patient management

“…Painful diabetic peripheral neuropathy (DPN) is one of the most commonly encountered chronic neuropathic pain syndromes in clinical practice. The first published description of pain in the setting of diabetes mellitus is more than 200 years old (Benbow et al ., 1999). It appears that any peripheral or cranial nerve in the body may be affected by DPN.…”

“…Diffuse symmetrical distal sensorimotor neuropathy is the most common manifestation of DPN and is thought to affect up to 34% of all patients with diabetes (Benbow et al ., 1999). Age at diagnosis, duration of diabetes and poor glycemic control correlate with the presence of DPN (Ziegler et al ., 1992).…”