Pain treatment satisfaction in spinal cord injury

Murphy, Douglas P.; Reid, DB

doi:10.1038/sj.sc.3101094

Cited by 54 publications

(32 citation statements)

References 2 publications

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“…The medication use by SCI subjects is typically high 8 and their satisfaction with their treatment reportedly low. 9 Tolerance and/or dependence may develop to some medication used in the control of pain 14 and anxiety/depression, 38 and since many SCI subjects are relatively young, long-term management of SCI needs new developments.…”

Section: Discussionmentioning

confidence: 99%

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The amelioration of the suffering associated with spinal cord injury with subperception transcranial electrical stimulation

et al. 2003

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Study design: Double blind, partial crossover. Objectives: To evaluate the analgesic activity of a novel cranial electrostimulus in people with spinal cord injury (SCI). Setting: Hereward College, a residential centre that provides educational facilities for students with disabilities. Methods: Subjects with SCI experiencing chronic pain were randomly assigned into two groups, one of which received sham and the other transcranial electrostimulation treatment (TCET) on two occasions daily for four successive days. After a`wash-out' period of 8 weeks all subjects returned and received the identical stimulus that the treated cohort received on the ®rst arm of the study. Results: Pain measurements applied before and after each session indicated that the pain decreased in the treated group to 51% of that reported at the commencement of treatment; reported pain intensity did not decrease signi®cantly in the sham treated subjects. The same (sham) subject group reported experiencing 59% of the pain at the end of the second arm of the study (TCET) as on the ®rst arm (sham). No signi®cant di erences were determined between the mood of all subjects estimated before and after each sham or TCET treatment session. The reported analgesic, and combined antidepressant and anxiolytic drug use in subjects receiving TCET on the second arm of the study, was 46% and 53% respectively of the average pre-study drug use. No similar decrease in the use of the drugs was noted in the same subjects after sham treatment on the ®rst arm of the study. Salivary cortisol determinations made prior to and after each sham and treatment session implicated this corticoid in the pain-relieving mode of action of the treatment, but could not be associated with any changes in mood. Subjects receiving TCET had signi®cantly higher urinary 3-methoxy-4-hydroxy-phenylglycol (MHPG) output after the TCET treatment period than sham stimulation, implicating increased central noradrenaline (NA) metabolism in the observed e ects. Conclusion: The subjects reported less pain during, and immediately after receiving this transcranial treatment, although they were using less medication than when receiving sham treatment.

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Section: Discussionmentioning

confidence: 99%

“…Consequently, subjects with SCI tend to be maintained on high doses and/or multiple medications from relatively young ages. 8 Satisfaction, however, in particular with analgesic e cacy, is reportedly low 9 and depression is frequently diagnosed 6,7 in SCI subjects.…”

Section: Introductionmentioning

confidence: 99%

The amelioration of the suffering associated with spinal cord injury with subperception transcranial electrical stimulation

et al. 2003

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“…Factors associated with poorer quality of sleep were analysed with the SAS logistic regression analysis for an ordinal response variable (SAS s , Release 8.2, SAS Institute Inc., USA). The six different sleeping items were classified into three response categories, no (1), mild (2-3), and severe (4)(5). Six logistic regression models were then performed with sleeping item as an ordinal response and pain (general and worst intensity, unpleasantness, intermittent, continuous), depression, and anxiety as covariates.…”

Section: Methodsmentioning

confidence: 99%

“…As one of the major consequences of SCI, pain has been found to affect quality of life, [1][2][3][4][5][6] leisure time activities, 5,7 vocational status, 7,8 and sexuality. 9 In non-SCI populations, poor sleep quality has been found in patients suffering from different health conditions such as obstructive pulmonary diseases, diabetes, rheumatic diseases, 10 and chronic pain conditions [11][12][13][14] as well as in patients suffering from affective disorders.…”

Section: Introductionmentioning

confidence: 99%

Quality of sleep in individuals with spinal cord injury: a comparison between patients with and without pain

2004

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Study design: A cross-sectional descriptive study of self-reported quality of sleep in individuals with a spinal cord injury (SCI). Objectives: To assess and describe subjective quality of sleep in patients with SCI, with and without pain. Setting: Spinalis SCI unit, Stockholm, Sweden. Methods: A total of 230 patients with an SCI were mailed a questionnaire containing queries about pain intensities, pain unpleasantness, mood, and sleep quality (Basic Nordic Sleep Questionnaire) to assess quality of sleep in patients with SCI with and without pain. Results: Of the 192 questionnaires that were returned (response rate 83.4%), 191 were analysed. Patients were divided into three groups: (1) those who reported no pain (n ¼ 50), (2) those who reported intermittent pain (n ¼ 42), and (3) those who suffered from continuous pain (n ¼ 99). Patients suffering from continuous pain rated pain intensity and unpleasantness significantly higher than those who only suffered from intermittent pain. The group with continuous pain also reported the poorest quality of sleep and the highest ratings of anxiety and depression of the three groups. Anxiety, together with pain intensity and depression, were the main predictors for poor sleep quality. Conclusions: Poor subjective sleep quality was associated with higher ratings of pain intensity, anxiety, and depression. It is possible that melatonin serves as a modulator of these different aspects. Sponsorship: This study was made possible by grants from Spinalis Foundation.Spinal Cord (2005) 43, 85-95.

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“…3,[5][6][7] Though NP is a significant issue for those with SCI, successful clinical management resulting in reduced pain intensity and improved function can be difficult to achieve and implement, 5,6,8 and evidence for best practices is limited. [9][10][11] The recent CanPainSCI Clinical Practice Guidelines (CPG) on the management of NP after SCI, [9][10][11][12] with recommendations on screening and diagnosis, treatment, and models of care, highlight many of these challenges.…”

Section: Introductionmentioning

confidence: 99%

Advancing research and clinical care in the management of neuropathic pain after spinal cord injury: Key findings from a Canadian summit

Loh

Guy

Craven

et al. 2017

Canadian Journal of Pain

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Background: Optimal management of neuropathic pain (NP) is essential to enhancing healthrelated quality of life for individuals living with spinal cord injury (SCI). A key strategic priority for the Ontario Neurotrauma Foundation (ONF) and Rick Hansen Institute (RHI) is optimizing NP management after SCI. Aims: A National Canadian Summit, sponsored by ONF and RHI, was held to develop a strategic plan to improve NP management after SCI. Methods: In a one-day meeting held in Toronto, Ontario, a multidisciplinary panel of 18 Canadian stakeholders utilized a consensus workshop methodology to (1) describe the current state of the field, (2) create a long-term vision, and (3) identify steps for moving into action. Results: A review of the current state of the field identified strengths including rigourously developed evidence syntheses and practice landscape documentation. Identified gaps included limited evidence on NP hindering recommendation development in evidence syntheses, absence of a national strategy, care silos with limited cross-continuum connections, limited consumer involvement, and limited practice standard implementation. The panel identified key themes for a long-term vision to improve the management of SCI NP in Canada, including establishing an integrated collaborative network; standardized care and outcome evaluation; education; advocacy; and directing resources to innovative solutions. The panel identified the next step as prioritization of areas that will have the greatest impact in a 5-year time frame. Conclusion: A strategic plan outlining a long-term vision to improve management of NP after SCI in Canada was developed and will inform future activities of the sponsors.

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Pain treatment satisfaction in spinal cord injury

Cited by 54 publications

References 2 publications

The amelioration of the suffering associated with spinal cord injury with subperception transcranial electrical stimulation

The amelioration of the suffering associated with spinal cord injury with subperception transcranial electrical stimulation

Quality of sleep in individuals with spinal cord injury: a comparison between patients with and without pain

Advancing research and clinical care in the management of neuropathic pain after spinal cord injury: Key findings from a Canadian summit

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