Pain relief in labour

Reynolds, F.

doi:10.1111/j.1471-0528.1993.tb15137.x

Cited by 17 publications

(2 citation statements)

References 41 publications

(31 reference statements)

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“…This is consistent with the previous studies. [9][10][11][12][13] Bitsch et al compared Tramadol with pethedin in labour analgesia and found identical analgesic efficiency in both the group. 14 Jain et al compared analgesic efficacy of intramuscular opioids: meperidine and tramadol with epidural analgesia.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of effectiveness of intermittent inhalational entonox in comparison with opioid tramadol for labour analgesia

Kumar¹,

Chandel

2017

Int J Reprod Contracept Obstet Gynecol

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INTRODUCTIONGiving birth is a painful process. Any intervention that leads to improvement in pain relief is worthy of investigation 1 . Opioid as well as epidural analgesia is effective means for pain relief in labour, notwithstanding their shortcomings. Data regarding Entonox (50% Nitrous Oxide and 50% Oxygen mixture) for labour analgesia is not available in current Indian literature. Use of Entonox offers many apparent advantages over the ABSTRACT Background:Childbirth is an emotion-filled event and the mother needs to bond with her newborn baby as early as possible. Any intervention that leads to improvement in pain relief is worthy of investigation. Entonox, opioids as well as epidural analgesia are effective means for pain relief in labour, notwithstanding their shortcomings. The objectives of study are to compare the effectiveness of intermittent inhalational Entonox for labour analgesia with intramuscular opioid (Tramadol) and to compare the effects of Entonox and Tramadol as labour analgesia on the maternal and fetal outcome of labour. Methods:The study was a prospective randomized, comparative study of two established techniques of labour analgesia. The study was carried out in 100 subjects. These subjects are divided into two groups. Group A -Tramadol Group: 50 women in active labour who received 100 mg tramadol intramuscularly with repeat dose of 50mg tramadol 4 hourly. Group B -Entonox Group: 50 women in active labour who received entonox for labour analgesia. Results:The mean VAS (visual analogue score) i.e. the pain score in group I (Tramadol) was 4.58±1.54 and Group II (Entonox) was 4.02±1.99 which is significantly low when compared to Group I (Tramadol) p<0.001. Study also showed that both the analgesics Entonox as well as Tramadol does not cause any significant change when compared for duration of labor. The rate of instrumental assisted vaginal deliveries and normal vaginal deliveries were almost equal in both the groups. In our study, the mean overall satisfaction level of the parturients in group II (Entonox) at 1 hr post delivery was (5.06±1.42) and 24 hr post delivery was (6.64±1.66) which was more when compared with tramadol group. The difference was statistically significant (p value was <0.001). This indicates that overall satisfaction level of the parturients is more with the use of Entonox when compared with Tramadol. Conclusions: Therefore, it is concluded that intermittent inhalational Entonox provides better labour analgesia then intramuscular opioid Tramadol.

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Section: Discussionmentioning

confidence: 99%

Evaluation of effectiveness of intermittent inhalational entonox in comparison with opioid tramadol for labour analgesia

Kumar¹,

Chandel

2017

Int J Reprod Contracept Obstet Gynecol

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“…Using paracetamol absorption, intramuscular pethidine was shown to cause a delay in gastric emptying in labouring women that was not reversible by metoclopramide 69 . This potentially may increase the risk of regurgitation and pulmonary aspiration and it has been recommended that histamine H 2 -antagonists be given to women who receive pethidine 70 . Additionally, intramuscular pethidine can cause depression of neonatal respiration and aspects of neonatal behaviour 71 .…”

Section: Adverse Effectsmentioning

confidence: 99%

Epidural Pethidine: Pharmacology and Clinical Experience

Kee

1998

Anaesth Intensive Care

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Pethidine is an effective epidural opioid for the treatment of acute pain. Its use has been well described in Australian and New Zealand practice, particularly in the field of obstetric anaesthesia. Reported methods of delivery have included bolus injection, continuous infusion and patient-controlled epidural analgesia. Areas of application have included treatment of postoperative pain, labour pain and intraoperative pain. Because of its intermediate lipid solubility, pethidine may have advantages over many other epidural opioids. However, potential for accumulation of norpethidine limits its use to relatively short durations of treatment.

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