Pain relief and motor function during continuous interscalene analgesia after open shoulder surgery: a prospective, randomized, double-blind comparison between levobupivacaine 0.25%, and ropivacaine 0.25% or 0.4%

Borghi, Battista; Facchini, Fiorenzo; Agnoletti, Vanni; Adduci, Angelina; Lambertini, A.; Marini, Elena; Gallerani, Pina; Sassoli, V; Luppi, Mario; Casati, Andrea

doi:10.1017/s0265021506000962

Cited by 28 publications

(19 citation statements)

References 13 publications

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“…When using continuous peripheral infusion of low concentration of ropivacaine for postoperative analgesia, ropivacaine showed a similar quality of pain relief as provided by bupivacaine65 or levobupivacaine 66. However, patients receiving ropivacaine consumed more local anesthetic than patients receiving levobupivacaine.…”

Section: Therapeutic Efficacymentioning

confidence: 93%

Update on the clinical utility and practical use of ropivacaine in Chinese patients

Li¹,

Wan²,

Mei³

et al. 2014

DDDT

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We reviewed the Chinese and English literature for efficacy and tolerability data as well as pharmacological properties of ropivacaine in Chinese patients. Ropivacaine is a long-acting amide local anesthetic agent that elicits nerve block via reversible inhibition of sodium ion influx in nerve fibers. The available evidence in the literature on anesthesia practice indicates that ropivacaine produces equally surgical sensory block and postoperative and obstetrics analgesia with good maternal and fetal outcome to those of bupivacaine or levobupivacaine. It appears to be associated with comparable onset, quality, and duration of sensory block, but with a lower incidence or grade of motor block, compared to bupivacaine. The satisfaction of both patients and surgeons is high when ropivacaine is used. Thus, ropivacaine appears to be an important option for regional anesthesia and for the management of postoperative and labor pain, with its enhanced sensorimotor differentiation blockage at lower concentrations and enhanced safety at higher concentrations.

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Section: Therapeutic Efficacymentioning

confidence: 93%

Update on the clinical utility and practical use of ropivacaine in Chinese patients

Li¹,

Wan²,

Mei³

et al. 2014

DDDT

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“…It was documented that 225 mg ropivacaine was considered equipotent to 150 mg levobupivacaine. [25] In patient-controlled continuous interscalene analgesia, Borghi et al [26] reported that 0.25% levobupivacaine provided similar quality of anesthesia as the one produced by equipotent (0.4%) concentration of ropivacaine, but better anesthesia than that with equivalent (0.25%) concentration in a similar clinical setting. It was showed that the onset and duration of nerve block induced by equimolar doses of 2 LAs were similar on isolated nerves.…”

Section: Discussionmentioning

confidence: 99%

Ropivacaine versus levobupivacaine in peripheral nerve block

Wei²,

Yang³

et al. 2017

Medicine

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Background: To determine which is more potent in peripheral nerve block between ropivacaine and levobupivacaine.Methods: A literature search was performed in the EMBASE, Medline, the Cochrane Library, and the Web of Science. The trials that were found were then evaluated for eligibility. The Cochrane Collaboration's Review Manager software was used to perform the meta-analyses.Results: Twelve studies including 556 patients were included for final analysis. No statistically significant difference was observed between the 2 drugs with respect to onset time of surgical anesthesia, onset time of sensory block, onset time of motor block, duration of motor block, and patients overall satisfaction. Levobupivacaine provided more long-term anesthesia (weighted mean difference [WMD], À2.94; 95% confidence interval [CI], À5.56 to À0.32; I 2 = 93%) and significantly lower incidence of postoperative rescue analgesia (odds ratio [OR], 2.11; 95% CI 1.18-3.74; I 2 = 21%) than ropivacaine. There was a trend toward greater duration of sensory block in the levobupivacaine group (WMD, À1.16; 95% CI, À1.89 to À0.43; I 2 = 14%).Conclusion: Levobupivacaine is more potent than ropivacaine in peripheral nerve block to some extent. Otherwise, more rigorous randomized control trials are required in the future.Abbreviations: CI = confidence interval, CNS = central nervous system, LA = local anesthetic, OR = odds ratio, WMD = weighted mean difference.

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“…When delivered via perineural catheters in various anatomic locations, ropivacaine appears to provide similar analgesia to bupivacaine as long as the dose is increased by approximately 50%. [150][151][152][153][154] In addition, although the evidence regarding motor block is mixed, [150][151][152]154,155 there is strong evidence that the duration of bupivacaine is 2 to 3 times that of ropivacaine. 155 Therefore, if ropivacaine is used for a perineural infusion and negatively influences mobilization, the infusion pump may be paused until resolution of the undesirable effects, allowing for more effective titration compared with a bupivacaine infusion.…”

Section: Ketaminementioning

confidence: 99%

Anesthesia and Analgesia Practice Pathway Options for Total Knee Arthroplasty

Kopp

Børglum

Buvanendran

et al. 2017

Regional Anesthesia and Pain Medicine

165

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In 2014, the American Society of Regional Anesthesia and Pain Medicine in collaboration with the European Society of Regional Anaesthesia and Pain Therapy convened a group of experts to compare pathways for anesthetic and analgesic management for patients undergoing total knee arthroplasty in North America and Europe and to develop a practice pathway. This review is intended to be an analysis of the current literature to assist individuals and institutions in designing a pathway for total knee arthroplasty that is based on existing evidence and expert recommendation and may be customized according to individual settings.

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Pain relief and motor function during continuous interscalene analgesia after open shoulder surgery: a prospective, randomized, double-blind comparison between levobupivacaine 0.25%, and ropivacaine 0.25% or 0.4%

Cited by 28 publications

References 13 publications

Update on the clinical utility and practical use of ropivacaine in Chinese patients

Update on the clinical utility and practical use of ropivacaine in Chinese patients

Ropivacaine versus levobupivacaine in peripheral nerve block

Anesthesia and Analgesia Practice Pathway Options for Total Knee Arthroplasty

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