Pain Reduction in Breast Augmentation Using Methocarbamol

Schneider, Marc S.

doi:10.1007/s002669900076

Cited by 24 publications

(11 citation statements)

References 1 publication

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“…It is, however, associated with considerable pain in the postoperative period, as we found in two previous studies [1,2]. Other authors have also described considerable postoperative pain after retromuscularly-placed implants [3], though pain has been more commonly evaluated after augmentation mammaplasty [4,5].…”

Section: Introductionmentioning

confidence: 77%

Placebo-controlled trial of local anaesthesia for treatment of pain after breast reconstruction

Legeby¹,

Jurell

Beausang‐Linder

et al. 2009

Scandinavian Journal of Plastic and Reconstructive Surgery and

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Breast reconstruction with submuscular tissue implants is associated with substantial postoperative pain. High pain scores despite large doses of opioids were described in earlier studies, which indicated that opioids alone or together with paracetamol are insufficient. In the present placebo-controlled study we aimed to evaluate the analgesic efficacy of local anaesthesia as a supplement. Forty-three women who had previously been operated on for breast cancer and were listed for unilateral secondary breast reconstruction were assigned at random to one of two groups. The patients received 2.5 mg/ml levobupivacaine (Chirocaine) 15 ml or placebo in a double-blind manner through an indwelling catheter in the operation site every three hours for 45 hours. All patients were given oral paracetamol 1 g x 4 orally and morphine intravenously as patient-controlled analgesia. A visual analogue scale (VAS) was used to assess the intensity of the postoperative pain. Amount of morphine used was recorded. The women in the levobupivacaine group (n=21) reported significantly less pain at rest during the first 15 hours postoperatively (p<0.05). During mobilisation the intensity of pain was lower for the first six hours (p=0.01) and for the interval 18-24 hours (p=0.045) in the same group. Total mean (SD) consumption of opioids in the levobupivacaine and placebo groups was 24.6 mg (22.88) and 33.8 mg (30.82), respectively (p=0.28). After reconstruction, levobupivacaine injected locally every third hour as a supplement to paracetamol orally and morphine given by PCA resulted in improved pain relief at rest and during mobilisation. Morphine consumption was reduced, but this was not significant (p=0.28).

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Section: Introductionmentioning

confidence: 77%

Placebo-controlled trial of local anaesthesia for treatment of pain after breast reconstruction

Legeby¹,

Jurell

Beausang‐Linder

et al. 2009

Scandinavian Journal of Plastic and Reconstructive Surgery and

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“…Considered a good treatment for muscle spasm [14], methocarbamol is a centrally acting muscle relaxant with a mildly sedating and anxiolytic effect at the central nervous system level [4]. This agent has a low likelihood for abuse [11], and has been used effectively in combination with narcotics for relief of postoperative chest pain after surgical placement of breast implants [12]. We found no particular complications attributable to the use of this drug.…”

Section: Discussionmentioning

confidence: 95%

Reduced hospitalization cost for patients with pectus excavatum treated using minimally invasive surgery

et al. 2003

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These data demonstrate for the first time that the use of an alternate pain management strategy including, narcotics, NSAIDs, and methocarbamol, but without epidural catheters, results in reduced hospital length of stay and decreased overall hospitalization costs for MIRPE, as compared with open pectus repair. This cost benefit was achieved without compromising pain management or patient satisfaction with surgical care.

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“…A few studies have assessed the effect of methocarbamol, but no prospective comparative studies have teen published. Pain relief was improved in 62 patients undergoing breast implant surgery with manipulation of the pectoralis major muscle by addition of methocarbamol to opioids 89 …”

Section: Muscle Relaxantsmentioning

confidence: 99%