Pain management in sports medicine: Use and abuse of anti-inflammatory and other agents

Derman, E W; Schwellnus, Martin

doi:10.1080/20786204.2010.10873927

Cited by 11 publications

(10 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Arachidonic acid is a substrate for cyclooxygenase (COX) and produces prostaglandins. This pathway and the substances produced in this cascade are responsible for pain and inflammation in sport-related injuries [7]. Generally, the initial treatment consists of rest, ice packs, compression and elevation of the affected limb in vertical plane (RICE) and administration of analgesics and antiinflammatories substances in order to limit the extent of inflammation and to alleviate the pain [2,3,14].…”

Section: Figure 1 Differences In Clinical Parameters Values In Day 14 From Baselinementioning

confidence: 99%

“…or i.m.) and topical administration of an NSAID is preferred [7]. The present study investigated the benefits of a combination with an NSAID (piroxicam 5 mg/g), an analgesic (cyclobenzaprine hydrochloride 5 mg/g) and a local anaesthetic (lidocaine 20 mg/g) in a single product for topical administration, PLC gel, to treat pain in musculoskeletal injuries in athletes, as monotherapy or associated with systemic analgesics versus a topical with a single NSAID used in the same conditions.…”

Section: Figure 1 Differences In Clinical Parameters Values In Day 14 From Baselinementioning

confidence: 99%

See 1 more Smart Citation

The Benefits and Risks of a Tricomponent Gel Containing Piroxicam, Lidocaine and Cyclobenzaprine, in Musculoskeletal Injuries in Athletes

Popescu¹

2018

FARMACIA

View full text Add to dashboard Cite

Sport-related injuries produces local inflammation, pain, oedema and local sensitivity. The pain is accompanied by impaired mobility and functionality and, in severe traumas, by disability. The present non-interventional study assessed the efficacy and safety of a topical combination of a NSAID (piroxicam 5 mg/g) with two sodium channel blockers anaesthetics (lidocaine 20 mg/g, cyclobenzaprine hydrochloride 5 mg/g) as a topical tricomponent gel (PLC) versus a topical gel only with a NSAID (piroxicam 10 mg/g) but in higher concentration, in the management of pain in sport related musculoskeletal injuries. The study was conducted on 90 rugby players from Romanian National Rugby Lot. The significant effectiveness of PLC gel was obvious from the first results in day 2: in the PLC gel group, pain on movement decreased by 17.91% and pain on pressure by 19.6% versus 9.28% and 10.12% respectively in the Piroxicam 1% gel group. Patients in the PLC gel group reported pain alleviation 15 minutes subsequent to topical application, and the effect lasted for an average of 11 hours. The effect of Piroxicam 1% gel was reported after an average of 52 minutes, but longer intervals of 80 minutes were also reported. The effect of Piroxicam 1% gel lasted up to 6 hours. The results from day 7 and then day 14 confirmed the superior efficacy of PLC gel versus Piroxicam 1% gel previously noticed in the results of the first visit. In day 14 in the PLC group pain alleviation increased by 70% considering both parameters, while in the Piroxicam 1% gel group it did not go beyond 45%. The analysis of the pain-free patients at the end of the treatment revealed an efficacy of 32% in pain on movement and 57% in pain on pressure in the PLC group and 2.32% in pain on movement and 6.97% in pain on pressure in the Piroxicam 1% gel group. RezumatTraumatismele sportive produc inflamație locală, durere, edem și sensibilitate locală. Durerea este însoțită de afectarea mobilității și funcționalității și, când traumatismul este suficient de sever, de dizabilitate. Studiul non-intervențional de față a evaluat eficacitatea și siguranța unei gel topic cu 3 componente (PLC) care conține un AINS (piroxicam 5 mg/g) și două anestezice blocante ale canalelor de sodiu (lidocaina 50 mg/g și ciclobenzaprina clorhidrat 5 mg/g), versus un gel pentru aplicare topică ce conține doar AINS-ul, dar în concentrație mai mare (piroxicam 10 mg/g), în managementul durerii din traumatismele musculoscheletice la sportivi. Studiul a inclus 90 de jucători de rugby din Lotul Național de Rugby al României. Eficacitatea semnificativ superioară a PLC gel a fost observată încă de la primele rezultate obținute la 2 zile de la începerea tratamentului: în grupul PLC gel durerea la mișcare a scăzut cu 17,91%, iar durerea la presiune cu 19,6% versus 9,28% respectiv 10,12% în grupul Piroxicam 1% gel. Pacienții din grupul PLC gel au raportat o ameliorare a durerii după 15 minute de la aplicare, iar efectul a durat în medie 11 ore. Instalarea efectului Piroxicam 1% gel a fost raportată în medie ...

show abstract

Section: Figure 1 Differences In Clinical Parameters Values In Day 14 From Baselinementioning

confidence: 99%

Section: Figure 1 Differences In Clinical Parameters Values In Day 14 From Baselinementioning

confidence: 99%

The Benefits and Risks of a Tricomponent Gel Containing Piroxicam, Lidocaine and Cyclobenzaprine, in Musculoskeletal Injuries in Athletes

Popescu¹

2018

FARMACIA

View full text Add to dashboard Cite

show abstract

“…In sports, medicine is a common usage or misusage of analgesic medications and NSAIDs [5]. Furthermore, Non-steroidal Anti-Inflammatory Drugs misuse is very common throughout International level football competitions in the African region.…”

Section: Introductionmentioning

confidence: 99%

“…In addition, the influence of ibuprofen to claim down pain throughout exercise is debatable and the impacts on endurance performance are unidentified [6]. Anesthetics are frequently used primarily to manage acute sport injuries to decrease pain [5]. Further, usage of the painkillers depends on the amount and time of discomfort.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Perceptions of Athletes about Usage of Painkiller Medications for Fatigue Slackening during Sport Trainings

Javed

Naseer

Gill

et al. 2021

JPRI

View full text Add to dashboard Cite

Objective: The purpose of the present research was to find out the perceptions of athletes about the usage of painkiller medications for fatigue relief while their sport trainings. Methodology: The data was collected from the athletes (n-80) having vast sport experiences who belonged to two public sector universities through online questionnaires. Afterwards, the collected data was edited into SPSS (v.26) and further analyzed the responses through descriptive statistics. Results: The majority of the athletes affirmed their intake of painkiller medications for the purpose of getting relief to their working group of muscles without claiming any harm or threat physically. Conclusion: These painkillers may be a source of less fatigue and provision of better blood flow to the working muscles of the athletes. Therefore, the athletes should use the painkillers with consultation of the doctor so that they may save themselves from their side effects if any.

show abstract

Pain control for traumatic musculoskeletal pain

Wang

2022

The American Journal of Emergency Medicine

View full text Add to dashboard Cite

Pain management in sports medicine: Use and abuse of anti-inflammatory and other agents

Cited by 11 publications

References 46 publications

The Benefits and Risks of a Tricomponent Gel Containing Piroxicam, Lidocaine and Cyclobenzaprine, in Musculoskeletal Injuries in Athletes

The Benefits and Risks of a Tricomponent Gel Containing Piroxicam, Lidocaine and Cyclobenzaprine, in Musculoskeletal Injuries in Athletes

Perceptions of Athletes about Usage of Painkiller Medications for Fatigue Slackening during Sport Trainings

Pain control for traumatic musculoskeletal pain

Contact Info

Product

Resources

About