Pain Management After Surgery: A Brief Review

Shoar, Saeed; Esmaeili, Sara; Safari, Saeid

doi:10.5812/kowsar.22287523.3443

Cited by 58 publications

(46 citation statements)

References 26 publications

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“…(3). Although at the present time opioids are the basis for postoperative pain control, because of the known side effects of these drugs a lot of efforts aremade to reduce the need for opioid doses in relieving pain after operations by administering other drugs or practicing other methods (3)(4)(5)(6). The ultimate purpose is to find non-opioid drugs with reasonable costs, lesser side effects and longer durability.…”

Section: Introductionmentioning

confidence: 99%

Effects of Single-Dose Pregabalin on Postoperative Pain in Dacryocystorhinostomy Surgery

Alimian¹,

Imani²,

Hassani³

et al. 2012

anesthpain

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Postoperative pain of dacryocystorhinostomy surgery is one of the serious issues to be considered. Utilizing other drugs instead of opioids can be an appropriate and practical solution in controlling the patients' pain. In this study we discuss effectivness of pregabalin in post-operative pain management in dacryocystorhinostomy surgery.Background: Postoperative pain of dacryocystorhinostomy (DCA) surgery is one of the serious issues to be considered. Administrating opioids to relieve postoperative pain and facing their increasing side effects in eye surgeries, make the use of non-opioid drugs inevitable. Objectives: The present study examined the efficacy of pregabalin in alleviating the postoperative pain of DCA surgery. Patients and Methods:The present study has been carried out as a double-blind, randomized clinical trial on the patient candidates for DCR. The patients were randomly divided in to two groups of pregabalin and placebo. Patients in pregabalin group received 300 mg of pregabalin, an hour before the operation in the morning of the surgery. Pain intensity on visual analog scale (VAS) was recorded until 24 hours after the operation; also the rate of administrated opioids and nausea/vomiting frequency were recorded during the first 24-hour period after the operation and the resultsof the two groups were compared. Results: Postoperative pain intensity in the pregabalin group at the time of recovery was significantly lower than that of the placebo group (P = 0.001) until 24 hours after the surgery. In the pregabalin group 17.5% of the patients received opioids while in the placebo group the figure was 52.5% (P = 0.001). Nausea frequency was also higher in the placebo group than the pregabalin group (P = 0.003). Conclusions: A single 300 mg dose of pregabalin, an hour before DCA can effectively reduce pain intensity and also reduce opioid dose and nausea/vomiting.

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Section: Introductionmentioning

confidence: 99%

Effects of Single-Dose Pregabalin on Postoperative Pain in Dacryocystorhinostomy Surgery

Alimian¹,

Imani²,

Hassani³

et al. 2012

anesthpain

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“…Pain after lower abdominal surgeries is a common occurrence and unless effective analgesia is provided many patients will have moderate to severe pain [2] . It is important to understand that severe pain may not only be responsible for secondary complications like hemodynamic instability, atelectasis (due to restricted respiratory movements) but also it may be responsible for delayed recovery, prolonged hospital stay, late ambulation and increased morbidity [3] .…”

Section: Jmscr Vol||06||issue||04||page 1268-1275||april 2018mentioning

confidence: 99%

A Comparative study of epidural Fentanyl with Bupivacaine & epidural Tramadol with Bupivacaine for post operative pain relief after lower abdominal Surgery

Patil¹

2018

jmscr

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“…Gabapentin has an analgesic (5) and opioid-sparing effect (1, 4, 6) both at rest and with movement (7) in acute postoperative pain management (1, 8-13). Postoperative pain is not purely nociceptive and may have other (inflammatory and visceral) components (14); so using drugs that act on different analgesic mechanisms seems logical (15-18).…”

Section: Introductionmentioning

confidence: 99%

Postoperative Gabapentin to Prevent Postoperative Pain: A Randomized Clinical Trial

Khahi¹,

Marashi²,

Khajavi³

et al. 2012

Anesth Pain

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BackgroundGabapentin is an anticonvulsant that has postoperative analgesic effects but there are limited studies on its postoperative administration.ObjectivesThe present study was conducted to evaluate the effect of the postoperative oral gabapentin on pain and morphine consumption.Patients and MethodsIn a double blind, randomized study, 64 patients undergoing internal fixation of tibia under spinal anesthesia were randomly assigned to receive oral gabapentin or placebo immediately after the surgery. Pain scores were recorded at time points of 2, 12 and 24 hours postoperatively using visual analog scale (VAS). Time duration from the end of surgery until morphine administration and total morphine requirement in the first 24 hours were recorded.ResultsThe estimated duration of surgeries was 120-150 minutes. VAS score was not significantly different between the two groups at 2, 12 and 24 hours after surgery. There was no significant morphine consumption difference between the groups.ConclusionsOur study showed no significant analgesic efficacy of oral gabapentin 300 mg immediately after tibia internal fixation surgery under spinal anesthesia at time points of 2, 12 and 24 hours postoperatively.

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Pain Management After Surgery: A Brief Review

Cited by 58 publications

References 26 publications

Effects of Single-Dose Pregabalin on Postoperative Pain in Dacryocystorhinostomy Surgery

Effects of Single-Dose Pregabalin on Postoperative Pain in Dacryocystorhinostomy Surgery

A Comparative study of epidural Fentanyl with Bupivacaine & epidural Tramadol with Bupivacaine for post operative pain relief after lower abdominal Surgery

Postoperative Gabapentin to Prevent Postoperative Pain: A Randomized Clinical Trial

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