Pain in patients with newly diagnosed or relapsed acute leukemia

Shaulov, Adir; Rodin, Gary; Popović, Gordana; Caraiscos, Valerie B.; Le, Lisa W.; Rydall, Anne; Schimmer, Aaron D.; Zimmermann, Camilla

doi:10.1007/s00520-018-4583-5

Cited by 17 publications

(11 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most pain syndromes experienced by multiple myeloma (MM) (62). Beyond MM, the same kind of skeletal lesions may also occur in the course of several advanced HM disease, although less commonly observed (64). Allogeneic HSCT patients might experience pain associated with GVHD-related mucosal damage, which has a similar appearance to that caused by cytotoxic drugs (65).…”

Section: Painmentioning

confidence: 99%

Supportive care and symptom management in patients with advanced hematological malignancies: a literature review

Chan

Gill

et al. 2022

Ann Palliat Med

View full text Add to dashboard Cite

Background and Objective: Recent advances have led to cure or long-term disease control for patients with hematological malignancy (HM). Unfortunately, some of them still have poor prognoses and are often associated with significant symptom burden and poor quality of life for patients and families. These patients usually require supportive care including red blood cell and platelet transfusion, due to disease itself and the oncological treatment, apart from their symptom management. However, there is currently lack of the literatures review in these aspects. The objective of this review is to summarize practical supportive care recommendations for physicians or nurses practicing in palliative care (PC)/hematology-oncology unit, starting with core approaches in use of blood products for anemia and thrombocytopenia, management of tumor lysis syndrome, PC and oncology nursing care.

show abstract

Section: Painmentioning

confidence: 99%

Supportive care and symptom management in patients with advanced hematological malignancies: a literature review

Chan

Gill

et al. 2022

Ann Palliat Med

View full text Add to dashboard Cite

show abstract

“…In the study; there was a weak negative correlation of age with nausea and vomiting symptoms and between BMI and loss of appetite; a weak positive correlation between the number of children and pain symptoms and between duration of diagnosis and loss of appetite symptom, and a weak negative correlation between duration of diagnosis and constipation symptom; a weak negative correlation between the duration of treatment and the cognitive functioning score, and a weak positive correlation with loss of appetite. According to Shaulov et al (2019), severe pain was associated with younger age, lower performance status, being diagnosed with ALL, and the time elapsed from the start of chemotherapy. Savcı (2006) determined that there is a weak negative relationship between age and perception of health, and as the duration of diagnosis and treatment increase, the overall score of the general QOL and SS level decreases.…”

Section: Discussionmentioning

confidence: 99%

Quality of Life and Social Support Levels in Leukemia Patients

Bıkmaz¹,

Ünsar²

2021

jgehes

View full text Add to dashboard Cite

This study aimed to determine the quality of life, level of social support, and its influencing factors in leukemia patients. Method: This descriptive cross-sectional study included 117 leukemia patients who applied to the Hematology Outpatient Clinic of a Medical Faculty Hospital in Istanbul. Data were collected using the Patient Information Form, European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 and Multidimensional Scale of Perceived Social Support. Normality analysis, descriptive statistics, difference analysis between pairs and multiple groups and correlation analysis were used in the analysis of the data. Results: It was determined that the global quality of life, functioning and symptom of leukemia patients were affected by personal and disease-related characteristics such as age, gender, number of children, Body Mass Index, marital status, educational status, type of leukemia, adaptation to the disease, and diagnosis, duration of treatment (p<0.05). It was determined that social support was positively correlated with the global quality of life and functioning scores of the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 and negatively correlated with the symptoms of loss of appetite and financial difficulties (p<0.05). Conclusion and Suggestions:Providing holistic care by nurses and taking into account the personal and disease-related characteristics of leukemia patients will improve their quality of life and social support level.

show abstract

“…64,92 Therefore, despite the high symptom burden and needs, clinician-initiated referral results in most patients diagnosed with HMs being referred very late or never to PC. 26,48 Interventions in most existing randomized controlled trials both in solid tumours and for HMs have consisted of routine referral for all patients shortly after the diagnosis of advanced disease (in solid tumours), 72 or shortly after admission for autologous or allogeneic haematopoietic stem cell transplantation or for acute leukaemia treatment. [17][18][19] Automatic referral to PC upon admission to hospital for treatment led to improved outcomes in two randomized controlled trials: one in HMs requiring stem cell transplantation and the other in acute leukaemia (Table 2).…”

Section: How Specialized Pc Referral Is Determined: Clinician-initiat...mentioning

confidence: 99%

“…The rollercoaster nature of life in the context of these diseases also presents unique challenges, both physical and psychological. While leukaemias do not commonly present as a compressive mass or nerve infiltration, pain is a prominent symptom due to multiple causes related to neutropenia and infection (e.g., perianal pain) as well as the result of treatment (e.g., mucositis, lumbar puncture) 26 . Patients with acute leukaemia report multiple burdensome physical and psychological symptoms, including lack of energy, drowsiness, dry mouth, pain, weight loss, difficulty sleeping, worrying, difficulty concentrating and feeling sad.…”

Section: Pc In Hmmentioning

confidence: 99%

Early integration of palliative care for patients with haematological malignancies

et al. 2022

Self Cite

View full text Add to dashboard Cite

Early palliative care (EPC) significantly improves quality of life, symptoms, and satisfaction with care for patients with advanced cancer. International organizations have recognized and promoted the role of palliative care as a distinct specialty, advocating its involvement throughout the cancer trajectory. Although patients with haematologic malignancies (HMs) have a comparable symptom burden to patients with solid tumours, they face multiple barriers to EPC integration. In this review, we discuss these barriers, present updated evidence from clinical trials of EPC in HMs and propose models to support EPC integration into care for patients with HMs.

show abstract

Pain in patients with newly diagnosed or relapsed acute leukemia

Cited by 17 publications

References 38 publications

Supportive care and symptom management in patients with advanced hematological malignancies: a literature review

Supportive care and symptom management in patients with advanced hematological malignancies: a literature review

Quality of Life and Social Support Levels in Leukemia Patients

Early integration of palliative care for patients with haematological malignancies

Contact Info

Product

Resources

About