Pain in COVID-19: Quis est culpa?

Abstract

<b>Background</b>: At present, during the coronavirus disease (COVID-19) pandemic, chronic pain is becoming more prominent, and it is also associated with the post-COVID-19 syndrome. Thanks to quick decisions on the therapy and as part of COVID-19 prevention, we have succeeded in stabilising the situation all over the world. On the other hand, ‘quick decisions’ have contributed to other significant issues which we are beginning to deal with now: in the effort to defeat the virus, many experts regarded the adverse effects of the medications used to be of secondary importance.<br /> <b>Purpose:</b> The article aims to demonstrate the side effects of treatment with various drugs (and their combinations) that are used to treat COVID-19 disease.<br /> <b>Method: </b>From the beginning of January until mid-May, the COVID-19 department of the 2nd Surgical Clinic of the Faculty of Medicine of the Comenius University in Bratislava (University Hospital Bratislava, Hospital of Saints Cyril and Methodius) treated 221 patients with moderate and severe course of COVID-19 (2nd wave of the pandemic). We saw some adverse effects and lack of effect of certain drugs for COVID-19.<br /> <b>Results: </b>The benefits of preventive measures compared to treatment are enormous. For example, corticoids can impair metabolism, cause diabetes, or suppress immunity. Antibiotics may cause colitis and blood pressure medications may negatively impact blood circulation.<br /> <b>Conclusion: </b>Preventive measures such as vaccination and activation of intrinsic antiviral immune systems are based on an incomparable benefit. Important in the process of the activation of antiviral immunity (linked to interferon synthesis) in the prevention of COVID-19 is the improvement of vitamin D deficit and the use of other micronutrients.<br /> <b>Practical value:</b> The results of the study will be valuable in the field of medicine, for virologists, pharmacologists, pharmacists, and medical professionals.

Case of Myocardial Infarction with Nonobstructive Coronary Arteries Caused by Thebesian Veins Thrombosis

“…As for the tactics of the management of this patient regarding a cardiac thrombus, most likely it is necessary to highlight two tactical points. First, if a fresh intracardiac thrombus was located in the area of trabeculae without lateral wall hypokinesis, it is possible, after examining the patient for thrombophilia, to start using antiplatelet agents with small doses of new oral anticoagulants (31,32). In the presence of hypokinesis of the left ventricle lateral wall, it is necessary to remember the possible damage not only to the fibrous capsule of the CA atherosclerotic plaque but also to the endomyocardium.…”

Біль І Можливості Фізіотерапії При Імпінджмент-Синдромі В Плечовому Суглобі

“…More are gradually added, in the middle of March 2020 in dozens a day [8][9][10][11][12]. Therefore, during this period, all patients were tested for SARSCoV2 and we counted on the risk of possible complications [13][14][15][16][17][18].…”

Antibiotic resistance and rational outpatient antibiotic treatment of upper respiratory tract infections in children

“…Це, наприклад, біль у місці ін'єкції, який може перерости в біль у цілій кінцівці, підвищення температури аж до лихоманки, оз ноб і тремтіння, головний біль, біль у м'язах і суглобах, слабкість, втома, нудота й інші. Такі реакції є легкими або помірними за інтенсивністю та зникають протягом кількох днів після вакцинації [30][31][32][33][34][35][36][37][38][39][40].…”

“…Профіль безпеки вакцин для профілактики захворю вання COVID19 переглядається щомісяця на місцевому рівні та на рівні Європейського Союзу [41]. На рівні Єв ропейського Союзу було виявлено, що профіль безпеки зареєстрованих вакцин здебільшого відповідає доку ментації лікарського засобу, а переваги вакцини значно перевищують будьякі потенційні ризики [39].…”