Pain as sign of recurrent disease in head and neck squamous cell carcinoma

Smit, Marjon A.; Balm, Alfons J. M.; Hilgers, F. J. M.; Tan, I. Bing

doi:10.1002/hed.1046

Cited by 40 publications

(34 citation statements)

References 11 publications

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“…They reported high level of problems in all the domains and rated their overall physical condition and overall quality of life as being poor, supporting the observation of previous study. 28 As stated by Smit et al 29 most patients with proven recurrent disease report pain complaints as the first symptom which was also observed in the present study. The authors also concluded that each pain complaint after intentional curative treatment should be regarded as a warning sign 29 and may reflect survival rate 30 but however, we can draw any certain conclusions from our study duty to limited sample size in this group of patients.…”

Section: Jaisani and Biliga Health Renaissance 2013; Vol 11 (No2);125-supporting

confidence: 88%

Quality of life and pain prevalence in postoperative patients with oral malignancy- a prospective longitudinal study

Jaisani

Baliga

2013

Health Renaissance

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Background: Epidemiology of pain in oral cancer patients, the effects of curative treatment on this pain, and the impact that the pain experience may have on the patient's quality of life is an overshadowed topic. Methods: A prospective and descriptive study on prevalence of pain, with its impact on quality of life (QOL) was carried out in 36 diagnosed cases of squamous cell carcinoma (SCC) of oral cavity, and were treated with a curative intension. QOL assessment was done using a questionnaire followed by clinical examination at 6months and 12 months post-treatment. Pain was assessed using memorial pain assessment card and pain faces. Results: 42 patients enrolled for this descriptive study but at the end of one year study period only 36 patients completed both the questionnaires. We observed that QOL in our patients, was significantly influenced by mode of soft tissue reconstruction, tongue mobility, speech intelligibility, cosmesis and oral competence. At 6months 16.7% patients reported no pain but at 12months this proportion increased to 52.8%. Severity of pain reduced significantly over time with significant improved pain relief. We observed significant correlation between pain, QOL and mood scale at 12months post-treatment. Conclusion:This study has clarified and statistically confirmed some principles on the residual QOL for patients treated by surgical resection and flap reconstruction for cancer of the oral cavity already presented in the literature. Pain is common among those presenting with curable head and neck cancer. Pain can be reduced by curative treatment.

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Section: Jaisani and Biliga Health Renaissance 2013; Vol 11 (No2);125-supporting

confidence: 88%

Quality of life and pain prevalence in postoperative patients with oral malignancy- a prospective longitudinal study

Jaisani

Baliga

2013

Health Renaissance

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“…An increasing number of studies focus on the quality of life (QOL) of SCCHN patients [3,15,17,18,19,24,25,26,27,28,29,30,31,32,33,34,35,38,39,40,41,42]. QOL is multifactorial and subjective, and improvement in cancer-related symptoms can be achieved through primary assessment and intervention for problems as they arise [15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35].…”

Section: Methodsmentioning

confidence: 99%

“…QOL is multifactorial and subjective, and improvement in cancer-related symptoms can be achieved through primary assessment and intervention for problems as they arise [15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35]. For example, the initial measurement of pain after treatment is more likely to predict pain status contributing to a decrease in the overall QOL after primary-stage SCCHN [3,15,17,18,19,24,25,26,27,28,29,30,31,32,33,34,35,38,39,40,41,42]. While such issues are clearly relevant, no studies have used qualitative methods to elucidate factors associated with the under-reporting of suffering in individuals in this patient population.…”

Section: Methodsmentioning

confidence: 99%

“…These include: (1) late presentation of disease [3,4,9,10]; (2) treatments for cure that still cause significant psychological and physical morbidity after curative treatment(s) [15,16,17,18,19,20,21]; (3) the continued consumption of alcohol and tobacco after the diagnosis and during treatment [1,2,3]; and (4) the occurrence of high-mortality second primary tumors, which arise at a rate of 1-4% per year. The last of these remains one of the more significant challenges to effective treatment in the long term, as the overall survival rates for SCCHN have not radically improved since the 1970s [3,15,16,22,23,24,25,26,27,28]. In addition, pain remains a common symptom in SCCHN patients and suffering has been underevaluated in patients with primary stage SCCHN [15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,…”

Section: Introductionmentioning

confidence: 99%

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A qualitative study of head and neck cancer

Moore

Chamberlain

Khuri

2004

Supportive Care in Cancer

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The findings presented contribute to quality of life (QOL) research by highlighting the significance of factors affecting the communication by patients with primary-stage squamous cell carcinoma of the head and neck cancer (SCCHN) of their experiences of suffering after treatment to their clinicians. Qualitative research methodology based on open-ended interviews with 18 survivors of American Joint Committee on Cancer primary stage I and II SCCHN were used. The interviews were transcribed verbatim and thematically analyzed. Three important themes emerged: (1). a diminished self (2). fears of addiction, and (3). hopelessness and the loss of meaning in life after SCCHN. The findings indicate that SCCHN patients under-report their experiences mainly due to fear. As a consequence, and perhaps due to a failure on the part of clinicians and patients to adequately address such fears, SCCHN patients may experience greater psychological morbidity, becoming increasingly fatalistic about biomedicine's ability to restore them to health after cancer despite being "cured", or to relieve related symptoms. This qualitative study provides a perspective as to why such under-reporting occurs, thereby potentially enhancing clinician-patient communication and the QOL of SCCHN patients who present with curable disease.

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“…Perineural spread of tumor was not observed in any patient on the MRI study. cause such referred pain [1][2][3][4][5][6]10]. The location of the disorder may thus be far more important than its etiology for this symptom.…”

Section: Resultsmentioning

confidence: 99%

Ear pain in patients with oropharynx carcinoma: how MRI contributes to the explanation of a prognostic and predictive symptom

et al. 2004

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Reflex otalgia is a predictive and prognostic parameter for local control in patients with oropharynx carcinoma. Can a morphologic correlate of this important symptom be detected by MRI? Thirty-six patients were prospectively evaluated by MRI before radical radiotherapy. Sixteen patients had reflex otalgia; 20 did not. The oropharynx and adjacent regions were analyzed. Alteration was defined as effacement of anatomical structures, signal alteration or enhancement after contrast medium administration. The χ 2 -test was used to compare categorical parameters. In patients with reflex otalgia, alteration of the following structures innervated by the glossopharyngeal nerve were found significantly more often: nasopharynx, hard palate, superior constrictor pharyngis muscle, palatine tonsil, palatopharyngeus muscle, palatoglossus muscle, stylopharyngeus muscle, hyoglossus muscle and preepiglottic space. No difference was found for the muscles of mastication, levator and tensor veli palatini muscles, styloglossus muscle, genioglossus muscle, intrinsic muscles of the tongue, digastric muscles, mucosal surface of the lateral and posterior pharyngeal wall, uvula, valleculae, parapharyngeal space and larynx. An alteration of structures innervated by the glossopharyngeal nerve was visualized on MRI significantly more often when reflex otalgia was present. Involvement of structures innervated by other cranial nerves did not show the same association with ear pain.

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Pain as sign of recurrent disease in head and neck squamous cell carcinoma

Abstract: This study confirms that each pain complaint after intentional curative treatment should be regarded as a warning sign. Recurrence of disease without preceding pain complaints (30%) emphasizes the importance of a thorough follow-up.

Cited by 40 publications

References 11 publications

Quality of life and pain prevalence in postoperative patients with oral malignancy- a prospective longitudinal study

Quality of life and pain prevalence in postoperative patients with oral malignancy- a prospective longitudinal study

A qualitative study of head and neck cancer

Ear pain in patients with oropharynx carcinoma: how MRI contributes to the explanation of a prognostic and predictive symptom

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