IMPORTANCEThere is debate about benefits of acupuncture for knee pain.OBJECTIVE To determine the efficacy of laser and needle acupuncture for chronic knee pain.
DESIGN, SETTING, AND PARTICIPANTSZelen-design clinical trial (randomization occurred before informed consent), in Victoria, Australia (February 2010-December 2012. Community volunteers (282 patients aged Ն50 years with chronic knee pain) were treated by family physician acupuncturists.
INTERVENTIONSNo acupuncture (control group, n = 71) and needle (n = 70), laser (n = 71), and sham laser (n = 70) acupuncture. Treatments were delivered for 12 weeks. Participants and acupuncturists were blinded to laser and sham laser acupuncture. Control participants were unaware of the trial. RESULTS At 12 weeks and 1 year, 26 (9%) and 50 (18%) participants were lost to follow-up, respectively. Analyses showed neither needle nor laser acupuncture significantly improved pain (mean difference; −0.4 units; 95% CI, −1.2 to 0.4, and −0.1; 95% CI, −0.9 to 0.7, respectively) or function (−1.7; 95% CI, −6.1 to 2.6, and 0.5; 95% CI, −3.4 to 4.4, respectively) compared with sham at 12 weeks. Compared with control, needle and laser acupuncture resulted in modest improvements in pain (−1.1; 95% CI, −1.8 to −0.4, and −0.8; 95% CI, −1.5 to −0.1, respectively) at 12 weeks, but not at 1 year. Needle acupuncture resulted in modest improvement in function compared with control at 12 weeks (−3.9; 95% CI, −7.7 to −0.2) but was not significantly different from sham (−1.7; 95% CI, −6.1 to 2.6) and was not maintained at 1 year. There were no differences for most secondary outcomes and no serious adverse events.
MAIN OUTCOMES AND MEASURES
CONCLUSIONS AND RELEVANCEIn patients older than 50 years with moderate or severe chronic knee pain, neither laser nor needle acupuncture conferred benefit over sham for pain or function. Our findings do not support acupuncture for these patients.TRIAL REGISTRATION anzctr.org.au Identifier: ACTRN12609001001280 JAMA. 2014;312(13):1313-1322. doi:10.1001/jama.2014 Author Audio Interview at jama.com
Related article page 1342Supplemental content at jama.com C hronic knee pain affects many people older than 50 years 1 and is the most common pain concern among older people consulting family physicians. 2 It is typically due to osteoarthritis and associated with declines in physical function. Nonpharmacological approaches are central to managing chronic knee pain. 3,4 Patients with joint pain and arthritis frequently use complementary and alternative medicine. 5 Acupuncture is the most popular of alternative medical systems, with use increasing over time. 5 Although traditionally administered with needles, laser acupuncture (low-intensity laser therapy to acupuncture points) is a noninvasive alternative with evidence of benefit in some pain conditions. 6-8 Efficacy of laser acupuncture compared with needles is unknown. Preliminary evidence suggests laser may be superior to needles for myofascial trigger points. 9 A meta-analysis supports needle acupuncture for osteoart...