Pain as a Predictor of Opioid Use Disorder in a Nationally Representative Sample

Blanco, Carlos; Wall, Melanie M.; Okuda, Mayumi; Wang, Shuai; Iza, Miren; Olfson, Mark

doi:10.1176/appi.ajp.2016.15091179

Cited by 74 publications

(66 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These findings are consistent with existing observational data on the associations of NMPOU and physical health co-morbidities (Alford et al, 2015; Blanco et al, 2016; Cicero et al, 2012b; Levi-Minzi et al, 2013; McCabe et al, 2007), and lends support to the idea that self-medication of untreated or under-treated health problems contributes to NMPOU. Although the present study did not collect information on motivation for NMPOU, Carlson and colleagues (2016) found that self-medication among NMPO users was not associated with heroin use initiation, whereas use to “get high” was.…”

Section: 0 Discussionsupporting

confidence: 90%

“…The selection of independent variables for examination was largely guided by recent findings in the scientific literature documenting associations between aspects of NMPOU and heroin use initiation (Carlson et al, 2016; Cicero and Ellis, 2015; Lankenau et al, 2012). Although the role of physical and mental health issues in transition to heroin is unclear, there are well-documented connections between pain, depression and the development of opioid use disorders (Blanco et al, 2016; Salas et al, 2016). As such, we included physical and mental health measures as independent variables in our analysis.…”

Section: 0 Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Heroin use onset among nonmedical prescription opioid users in the club scene

Surratt

Kurtz

Buttram

et al. 2017

Drug and Alcohol Dependence

View full text Add to dashboard Cite

Background Nonmedical prescription opioid use (NMPOU) is well documented among participants in the club scene, yet prior studies have not examined transition to heroin use. We prospectively examined heroin initiation among a sample of young adults with drug involvement associated with participation in the club scene, to understand factors that influence transition from NMPOU to heroin and to identify opportunities for intervention. Methods Data were drawn from a randomized trial that enrolled 750 Miami-based club and prescription drug users through respondent driven sampling, and tested the efficacy of assessment interventions in reducing risk. Participants reported current substance use at baseline, 3, 6, and 12 month follow-ups. We examined predictors of heroin initiation among participants reporting NMPOU at baseline, with no lifetime history of heroin use (N=323). Results The mean age was 25.0 years; 67.5% met DSM-IV criteria for substance dependence. About 1 in 13 participants (7.7%) initiated heroin use at follow-up. In univariable comparisons, frequent LSD use, history of drug overdose, high frequency NMPOU, using oral tampering methods, and endorsing a primary medical source for prescription opioids were associated with greater likelihood of heroin initiation. LSD use, oral tampering, and primary medical source were significant predictors in a Cox regression model. Conclusions Heroin initiation of 7.7% suggests a high level of vulnerability for transition among young adult NMPO users in the club scene. The importance of oral tampering methods in the trajectory of NMPOU may indicate a need to further examine the role of abuse deterrent formulations in prevention efforts.

show abstract

Section: 0 Discussionsupporting

confidence: 90%

Section: 0 Methodsmentioning

confidence: 99%

Heroin use onset among nonmedical prescription opioid users in the club scene

Surratt

Kurtz

Buttram

et al. 2017

Drug and Alcohol Dependence

View full text Add to dashboard Cite

show abstract

“…Further, men who had immediate family members who engaged in prescription drug misuse were nearly seven times more likely to also engage in NMUPO. Results from our study extend previous findings by providing evidence that in addition to illicit substance misuse (Liebschutz et al, 2010; Blanco et al, 2016), prescription drug misuse among immediate family increases likelihood of NMUPO.…”

Section: Discussionsupporting

confidence: 84%

“…Liebschutz and colleagues (2010) found that among a majority African American sample of adults, family history of illicit drug misuse was associated with greater odds of prescription drug misuse. Blanco and colleagues (2016) found similar results using a nationally representative adult sample. However, neither of these studies examined family history of prescription drug misuse specifically, but rather examined illicit drug use among family members.…”

Section: Introductionsupporting

confidence: 65%

Culturally relevant risk and protective factors for nonmedical use of prescription opioids among incarcerated African American men

Wheeler

Stevens‐Watkins

Moody

et al. 2019

Addictive Behaviors

View full text Add to dashboard Cite

Background: Recent studies have demonstrated that nonmedical use of prescription opioids (NMUPO) is a national phenomenon affecting a multitude of subpopulations, including incarcerated African American men. However, there has been little investigation of the correlates of NMUPO among this population. Objective: Grounded in primary socialization theory, the current study aimed to examine the association between family bonds, family history of prescription drug misuse, and mental health symptoms on NMUPO among African American incarcerated men. Method: A step-wise logistic regression was conducted to determine whether family and mental health factors affected the likelihood of lifetime NMUPO. Results: Prescription drug misuse among immediate family members (p < .001) and lifetime experience of serious anxiety (p = .003) were significantly associated with an increased likelihood of NMUPO. Having a close personal relationship with one’s father was significantly associated with a decreased likelihood of NMUPO (p = .034). Conclusions/Importance: Risk and protective factors are identified that can be incorporated into interventions aimed at reducing or preventing NMUPO among African American men. Directions for future research on NMUPO among African American incarcerated men are discussed.

show abstract

“…More specifically, the study used data from 16 years of the National Health and Nutritional Examination Survey (NHANES) for years 1999 to 2014 to examine trends in use of prescription opioids as well as long‐term use of opioids. In addition, associations of long‐term use with indicators of elevated risk of adverse effects from opioid treatment were examined, including presence of painful conditions, severe medical conditions, concomitant use of benzodiazepines, and history of heroin and alcohol misuse …”

Section: Introductionmentioning

confidence: 99%