Paget’s Disease with Spinal Cord Compression

Abstract

Two cases with spinal cord compression due to Paget’s disease (osteodystrophia deformans) are reported, which were treated with calcitonin (Salmon Calcitonin) during 12 and 24 months after decompressive laminectomy. Both presented a favourable clinical course with improvement of sensory and bladder disturbances, paraparesis and pain. Diagnostic criteria as X-ray investigation, scintigraphy of bones, biochemical parameters and the long-term treatment with calcitonin, are discussed.

Spinal cord function in Paget's disease of spine

“…Further, even when laminectomy has been performed the recovery is seldom rapid. The subsequent administration of calcitonin after decompression resulted in rapid neurologic gains in at least three cases (Schumacher et al, 1977;Ravichandran, 1979).…”