Paget's disease of Pelvis Mimicking Metastasis in A Patient with Prostate Cancer

Abstract

Paget’s disease of bone is a benign disease, of uncertain etiology, characterized by an accelerated turnover, that is, bone resorption and formation. Paget’s disease may be present in up to 5% of the population, and the majority of cases are asymptomatic. We report the imaging findings of Paget’s disease of pelvis discovered incidentally in a 70 year old patient with prostatic adenocarcinoma, who underwent an MRI (magnetic resonance imaging) for the staging of his disease and revealed extensive marrow signal abnormalities at the left pelvic bone. Biochemical tests revealed normal serum calcium and phosphorus with markedly raised alkaline phosphatase. X-RAYS and CT SCANS of the pelvis show cortical and trabecular thickening of the left iliac bone that are typical for this disease. Furthermore, increased uptake noted in left hemipelvis suggestive of Paget's disease on the scintigraph. After the treatment the uptake in left hemipelvis remains same confirming Paget's disease.