Paediatric supra- and infratentorial multiple giant clear cell meningioma: A report of a rare case and review of the literature

Tan, Xuan-Yu; Wang, Yübo; Jiang, Wei; Cao, Yilin; Teng, Yongliang; Zhao, Gang

doi:10.1007/s00381-020-04975-y

Cited by 2 publications

(1 citation statement)

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“…Cases of PM that occur after oncological treatment during childhood with several types of radiation-induced tumors have been reported in pediatric patients. Meningioma is the second most common radiation-induced tumor in children [12, 13]. Radiation-associated meningiomas are often aggressive and likely to be multiple; they also have a high recurrence rate [14].…”

Section: Introductionmentioning

confidence: 99%

Pediatric Cerebral Meningioma: A Single-Center Study with 10 Children Not Associated with Neurofibromatosis Type 2 and Literature Review

Opoku¹,

Yang²,

Sun³

et al. 2022

Pediatr Neurosurg

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Introduction: Pediatric meningiomas are rare tumors, they differ from their adult counterparts by their atypicality of location, higher rates of malignant change, male preponderance, recurrence and sometimes their association with neurofibromatosis. This case series analyzes the clinical behavior, pathological presentation, location and its association with Neurofibromatosis type 2 (NF2). Methods: This case series consists of pediatric patients between the ages of 4 and 16 years who were hospitalized in the neurosurgical department of our hospital from 2012 to 2021 with different neurological symptoms and a literature view using PubMed/Medline database. Results: 60% of the patients were males whiles 40% were females. The most common neurological manifestation were signs of increased intracranial pressure. NF2 was absent in all patients. The predominant histopathology subtype is Atypical and WHO Grade II representing 30% and 40% respectively. Conclusion: This study supports the relationship between NF2 and pediatric cerebral meningioma but at a lower concomitant rate from 0 to 13% taking into consideration our original data and the literature review, contrasting some reported cases which suggest rates as high as 33%, 50% and 100% in a very small number of patients. Gross total resection (GTR) without post operatory radiation therapy for non-malignant and non NF2 associated pediatric meningioma (PM) proved to be a sufficient and a good treatment option.

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Section: Introductionmentioning

confidence: 99%