Paediatric Prescription Analysis in a  Primary Health Care Institution

Jose, Jinish; Devassykutty, Denny

doi:10.7860/jcdr/2016/22350.8797

Cited by 7 publications

(13 citation statements)

References 11 publications

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“…In this study, the average number of drugs per prescription was 2.56. Similar results were found in Oman (2.3; 2.88) [4,17], Pakistan (2.34) [18], Maharashtra (2.35) [19], India (2.29) [20] and Italy (2.9) [21]. Higher values were found in Sierra Leone (3.77) [8], Nepal (4.5) [22] and Nigeria (3.5; 3.8) [7].…”

Section: Discussionsupporting

confidence: 82%

Evaluation of Prescribing Indicators in a Paediatric Population Seen in an Outpatient Consultation at the Gaspard Kamara Health Centre in 2019 (Senegal)

et al. 2021

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Introduction: Data on drug use in paediatrics are scarce in Senegal. The objective of this study was to assess the prescribing indicators in a paediatric population seen in an outpatient consultation at a Health Centre in Dakar, Senegal. Methods: A retrospective and analytical study was conducted. The study population consisted of prescriptions for children aged 0 to 14 years who were seen in ambulatory consultation between 1 June and 30 November 2019. The sample size was 600 prescriptions. The systematic survey was then conducted. Five prescription indicators recommended by the World Health Organization were calculated. The R software was used for descriptive analysis, bivariate analysis and binomial logistic regression. Results: The average number of drugs per prescription was 2.56. The proportion of drugs prescribed under the International Nonproprietary Name (INN) was 18.9%, while the proportion of drugs on the National Essential Medicines List (NEML) was 41.3%. The proportions of prescriptions with at least one antibiotic and one injectable product were 41.5% and 1.3%, respectively. Conclusions: This study showed that prescribing habits were inadequate. Thus, it would be necessary to move towards continuing training of prescribers in the wise use of medicines.

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Section: Discussionsupporting

confidence: 82%

Evaluation of Prescribing Indicators in a Paediatric Population Seen in an Outpatient Consultation at the Gaspard Kamara Health Centre in 2019 (Senegal)

et al. 2021

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“…Five out of those ten main therapeutic classes were similar with our study (analgesics, emollient, dermatological corticosteroid, nasal preparation, and cough and cold preparations). Similar to other studies, respiratory system disorder was the primary indication for medication use in our study [10,17,22,28].…”

Section: The Most Common Therapeutic Classes and The Reasons For Usagesupporting

confidence: 89%

“…The predominance of oral drug formulation in our study (90.5%) was also seen in other previous similar studies [10,13,22,23]. Oral liquid formulations are widely used among young children since they are easier to swallow than the solid form [24].…”

Section: Formulation and Durationsupporting

confidence: 88%

“…Considering this advantage, prescribers should be aware of any potential drug interactions when prescribing drug combination in their practice [25,26]. Rectal, inhalation, and injections were less frequently used in this study, and also in other studies [10,13,22,23]. Median duration of medication use per child in this study was 3.67 days (ranged between 1 to 63 days).…”

Section: Formulation and Durationmentioning

confidence: 79%

“…Reasons for mediation use (respiratory disorders, gastrointestinal disorders, unspecified pyrexia), participant's age older than 4 months when using the medication, oral drug formulation and inpatient care setting were strongly associated with the number of non-antibiotic drug regimen. Respiratory disorders, gastrointestinal disorders, and unspecified pyrexia manifest as multiple symptoms thus may encourage child caretakers to self-medicate the children with multiple over-the-counter (OTC) [10,22]. Hospitalized child may also indicate a more complex diagnosis to be treated, thus more medications may be required [10].…”

Section: Number Of and Factors Associated With Non-antibiotic Drug Rementioning

confidence: 99%

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Non-antibiotic medication use in an Indonesian community cohort 0–18 months of age

et al. 2020

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Background Rational medication use for treatment is mandatory, particularly in children as they are vulnerable to possible hazards of drugs. Understanding the medication use pattern is of importance to identify the problems of drug therapy and to improve the appropriate use of medication among this population. Methods A post-hoc study of the RV3-BB Phase IIb trial to children aged 0–18 months which was conducted in Indonesia during January 2013 to July 2016. Any concomitant medication use and health events among 1621 trial participants during the 18 months of follow-up were documented. Information on medication use included the frequency, formulation, indication, duration of usage, number of regimens, medication types, and therapeutic classes. Results The majority of participants (N = 1333/1621; 82.2%) used at least one non-antibiotic medication for treatment during the 18-month observation period. A total of 7586 medication uses were recorded, mostly in oral formulation (90.5%). Of all illnesses recorded, 24.7% were treated with a single drug regimen of non-antibiotic medication. The most common therapeutic classes used were analgesics/antipyretics (30.1%), antihistamines for systemic use (17.4%), cough and cold preparations (13.5%), vitamins (8.6%), and antidiarrheals (6.6%). The main medication types used were paracetamol (29.9%), chlorpheniramine (16.8%), guaifenesin (8.9%), zinc (4.6%), and ambroxol (4.1%). Respiratory system disorder was the most common reason for medication use (51.9%), followed by gastrointestinal disorders (19.2%), pyrexia (16.9%), and skin disorders (7.0%). Conclusion A large number of children were exposed to at least one medication during their early life, including those where evidence of efficacy and safety in a pediatric population is lacking. This supports the need for further research on pediatric drug therapy to improve the appropriate use of medication in this population.

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Prescription Practices and Outcome Analysis of PICU Patients at a Newly Established Tertiary Care Hospital—A Retrospective Study

Chalissery,

Eerike,

Samprati

et al. 2023

J Pediatr Intensive Care

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Prescription analysis studies play a crucial role in monitoring prescription patterns and establishing guidelines for effective drug delivery and health care management. Given the physiological differences between the pediatric and adult populations, it is essential to analyze the prescription records specifically for pediatric patients, considering their unique diseases, drugs, and dosages. The objectives of this study were to analyze the prescribing patterns of drugs, rationality, outcomes, and antimicrobial use and drugs from National List of Essential Medicines (NLEM) in pediatric intensive care unit (PICU) patients. A retrospective study design was employed, and data were collected from medical records, including demographic information, diagnoses, drug details, and treatment outcomes of PICU patients. The collected data were then analyzed according to the World Health Organization (WHO) indicators for rational drug use, WHO Access, Watch, and Reserve (AWaRe) guidelines for antimicrobial use, and the proportion of essential drugs prescribed. Descriptive statistics was used to express the data in this study. A total of 184 patient records were analyzed, with 57.6% were males. On average, 4.5 drugs were prescribed per prescription, with injections and syrups comprising nearly 28% each. Approximately 71.5% of prescriptions contained generic drug names. Furthermore, 49% of the prescribed drugs were listed in the NLEM. Antibiotics were present in 50% of the prescriptions, with 50% of them falling under the WHO AWaRe Watch category and 31% in Access category. Majority of the drugs being prescribed in the PICU were with generic names, and less than half the prescriptions contained antibiotics. Watch class of antibiotics was most commonly prescribed.

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Paediatric Prescription Analysis in a Primary Health Care Institution

Cited by 7 publications

References 11 publications

Evaluation of Prescribing Indicators in a Paediatric Population Seen in an Outpatient Consultation at the Gaspard Kamara Health Centre in 2019 (Senegal)

Evaluation of Prescribing Indicators in a Paediatric Population Seen in an Outpatient Consultation at the Gaspard Kamara Health Centre in 2019 (Senegal)

Non-antibiotic medication use in an Indonesian community cohort 0–18 months of age

Prescription Practices and Outcome Analysis of PICU Patients at a Newly Established Tertiary Care Hospital—A Retrospective Study

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