Paediatric GI emergencies

Saliakellis, Efstratios; Borrelli, Osvaldo; Thapar, Nikhil

doi:10.1016/j.bpg.2013.08.013

Cited by 13 publications

(14 citation statements)

References 134 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The main causes of GIP in pediatric patients include meconium ileus, atresia, volvulus, Meckel diverticulum, necrotizing enterocolitis, appendicitis, intussusception, inflammatory bowel disease, peptic ulcer, other gastrointestinal diseases causing obstruction, foreign body ingestion, iatrogenic injury and trauma [1234]. Moreover, the pattern of causes changed from obstruction, trauma, peptic ulcer to necrotizing enterocolitis, iatrogenic injury, perinatal asphyxia events, and others [10]. However, SGIPs are not associated with these conditions and are usually only described in sporadic case reports.…”

Section: Discussionmentioning

confidence: 99%

Clinical implication of spontaneous gastrointestinal perforation in pediatric patients: its difference according to age group

et al. 2018

View full text Add to dashboard Cite

PurposeSpontaneous gastrointestinal perforations (SGIPs; not associated with injury or disease) occur rarely in pediatric patients. This study aimed to define age-specific features associated with SGIPs in pediatric patients.MethodsRetrospectively reviewed the clinical data of children (before adolescence) who received surgery due to a SGIP at a single institution. Thirty-nine patients were enrolled. Characteristics were compared between the 2 age groups: neonates (group A) and beyond neonates (group B).ResultsGroup A included 24 patients (61.5%) an group B included 15 patients (38.5%). Thirteen perforations occurred in the stomach (33.3%), 12 in the small intestine (30.8%), and 14 in the large intestine (35.9%). A significantly higher proportion of perforations occurred in the stomach and small intestine in group A, while more perforations occurred in the large intestine in group B (P = 0.01). Several associated conditions during the preoperative period were identified in both groups. The overall mortality rate was 15.4% (6 of 39). Mortality was relatively high in group A (5 of 24, 20.8%) and for perforations of stomach (3 of 13, 23.1%) and small intestine (3 of 12, 25.0%); however, there were no significant differences with regard to age or perforation site (P = 0.244, P = 0.122, respectively).ConclusionSGIPs in pediatric patients had diverse clinical features and different perforation patterns according to age group. However, no significant group differences in mortality were found. Thus, favorable results regardless of age can be expected with prompt recognition, medical resuscitation, and adequate surgical management.

show abstract

Section: Discussionmentioning

confidence: 99%

Clinical implication of spontaneous gastrointestinal perforation in pediatric patients: its difference according to age group

et al. 2018

View full text Add to dashboard Cite

show abstract

“…The ingestion of foreign bodies most frequently occurs in children (1–3 years old) 2 . In adulthood this is seen in psychotic patients, 2 but it is a rare, mostly accidental event, in normal population, mainly occurring due to food bones’ ingestion.…”

Section: Discussionmentioning

confidence: 99%

“…In adulthood this is seen in psychotic patients, 2 but it is a rare, mostly accidental event, in normal population, mainly occurring due to food bones’ ingestion. Perforation of the duodenum, and small bowel have been reported for trichobezoar obstruction or sponge obstruction.…”

Section: Discussionmentioning

confidence: 99%

Upper G.I. hemorrhage from glass fragments’ ingestion in a patient with jejunal diverticula – Case report

Gattai

Pantalone

Migliaccio

et al. 2015

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

show abstract

“…The vast majority of cases in children are due to either acute appendicitis (AA) or acute mesenteric lymphadenitis (AML) (Khanna et al, 1983;Macari et al, 2002;Mandell et al, 2009;Yoon et al, 2002;Hayes, 2004). The incidence of AA is 25 cases per 10 000 paediatric patients per year between the ages of 10 and 17 years in the United States (Yoon et al, 2002;Saliakellis et al, 2013;Wray et al, 2013). The discharge diagnosis was primary AML in 7-20% of paediatric patients with a clinical suspicion of AA (Macari et al, 2002;Sicorska-Wiúneiewska et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

“…In the case of AML, treatment is more conservative and does not require hospitalisation (Khanna et al, 1983;Macari et al, 2002;Hayes, 2004;Toorenvliet et al, 2011) while in the case of AA immediate hospitalisation is mandatory and with perhaps further surgery (Wray et al, 2013). Missing the diagnosis of AA in the emergency department may increase the probability of perforation of the appendix as well as the rate of other complications (Yoon et al, 2002;Chang et al, 2010;Saliakellis et al, 2013;Wray et al, 2013). The rate of perforated appendicitis has been reported as high as 10-20% in children 10-17 years of age (Wray et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Different Cytokine Profiles in Children with Acute Appendicitis and Acute Mesenteric Lymphadenitis / Atðíirîga Citokînu Grupas Seruma Iekaisuma Mediatoru Izpausme Akûta Apendicîta Un Akûta Mezenteriâla Limfadenîta Gadîjumâ Bçrniem

Zviedre

Eòìelis

Tretjakovs

et al. 2015

Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.

View full text Add to dashboard Cite

The aim of this study was to investigate the role of serum cytokines in the diagnosis of acute appendicitis (AA) and acute mesenteric lymphadenitis (AML). Data were collected prospectively on 7 to 18 year old children (October 2010 - October 2013): 31 patients with AA, 26 patients with AML, and 17 patients with elective non-inflammatory surgical disease were selected as controls. Serum levels of IL-10, IL-12(p70), IL-1β, IL-4, IL-6, IL-8, IL-17, MCP-1, EGF, TNF-α were measured. Patients with AA had significantly increased serum levels of IL-6(1) (z = -3.72; p = 0.0002) and IL-10(1) (z = -2.81; p = 0.005) compared to AML before any treatment. The consecutive measurements of MCP-1 in serum demonstrated a significant difference within 72 hours in the AA group (Wilks’ Lambda test 0.80; F(2;29) = 3.5; p = 0.04) and also in the AML group (Wilks’ Lambda test 0.70; F(2;24) = 5.0; p = 0.01). The increased values of IL-6 and IL-10 were the most reliable cytokines one hour before surgical intervention for patients with AA. MCP-1 values changed significantly within 72 hours after patient hospitalisation but did not differ between the groups, and could not be a helpful serum biomarker in distinguishing patients with AA and AML.

show abstract

Paediatric GI emergencies

Cited by 13 publications

References 134 publications

Clinical implication of spontaneous gastrointestinal perforation in pediatric patients: its difference according to age group

Clinical implication of spontaneous gastrointestinal perforation in pediatric patients: its difference according to age group

Upper G.I. hemorrhage from glass fragments’ ingestion in a patient with jejunal diverticula – Case report

Different Cytokine Profiles in Children with Acute Appendicitis and Acute Mesenteric Lymphadenitis / Atðíirîga Citokînu Grupas Seruma Iekaisuma Mediatoru Izpausme Akûta Apendicîta Un Akûta Mezenteriâla Limfadenîta Gadîjumâ Bçrniem

Contact Info

Product

Resources

About