Paediatric bowel ultrasound in inflammatory bowel disease

Elliott, Claire; Maclachlan, Jody; Beal, Isobel

doi:10.1016/j.ejrad.2018.09.004

Cited by 13 publications

(14 citation statements)

References 30 publications

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“…Monitoring will continue to include BMI, growth and development in addition to such other objective measures as faecal calprotectin(FC), C-reactive protein, colonoscopy and cross-sectional imaging. Transabdominal ultrasonography is especially suitable for transitioning patients because it is non-invasive, cost effective and radiation-free [27,28]. Of note, transition patients must be responsible for such monitoring tools as FC.…”

Section: Transition Models and Timingmentioning

confidence: 99%

Can a transition clinic bridge the gap between paediatric and adult inflammatory bowel disease care models?

Nardone

Iacucci

Ghosh

et al. 2020

Digestive and Liver Disease

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Section: Transition Models and Timingmentioning

confidence: 99%

Can a transition clinic bridge the gap between paediatric and adult inflammatory bowel disease care models?

Nardone

Iacucci

Ghosh

et al. 2020

Digestive and Liver Disease

View full text Add to dashboard Cite

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“…All the US examinations were performed by one of the two paediatric radiologists with more than 10 years of experience in bowel US, using Xario TM 200 (Cannon Medical Systems Corporation, Otawara, Japan) or Aplio 500 machine (Canon Medical Systems Corporation, Otawara, Japan) with linear (7-14 MHz) and convex (4-6 MHz) transducers, without oral contrast medium administration. The investigation protocol included systematic evaluation of the abdomen starting with the intra-abdominal solid organs using a low frequency convex probe, with the patient lying supine [27]. For a better examination of the large bowel, the high frequency linear probe [39] with graded compression [40] was used, starting at the caecum in the right iliac fossa, after the localization of the terminal ileum and progressing distally for the evaluation of ascending, transverse, descending and sigmoid colon [27].…”

Section: Abdominal Usmentioning

confidence: 99%

“…The investigation protocol included systematic evaluation of the abdomen starting with the intra-abdominal solid organs using a low frequency convex probe, with the patient lying supine [27]. For a better examination of the large bowel, the high frequency linear probe [39] with graded compression [40] was used, starting at the caecum in the right iliac fossa, after the localization of the terminal ileum and progressing distally for the evaluation of ascending, transverse, descending and sigmoid colon [27]. Representative images from each bowel segment, normal or pathological (fig 1 and 2), were stored in each case in the Picture Archiving Communication System (PACS), as the standard protocol of our hospital requires.…”

Section: Abdominal Usmentioning

confidence: 99%

“…The images stored in PACS were analysed individually by the two radiologists, blinded to the result of the colonoscopy, value of FC and PUCAI. In all bowel segments the following parameters were evaluated: BWT (normal value <3 mm for all segments), bowel vascularity (using power Doppler), presence of lymphadenopathies and mesenteric inflammatory fat, following the published protocols [27,41]. In case of disagreement between the examiners, the images were reviewed and conclusion was reached by consensus.…”

Section: Abdominal Usmentioning

confidence: 99%

“…Abdominal ultrasound (US) is a non-invasive, low cost, accessible, reproductible and easily accepted by children imaging technique, used more and more frequently in the recent years in assessing bowel inflammation [27,28]. It is largely used in clinical practice for abdominal complaints or check-up examinations.…”

Section: Introductionmentioning

confidence: 99%

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The value of abdominal ultrasonography compared to colonoscopy and faecal calprotectin in following up paediatric patients with ulcerative colitis

et al. 2021

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Aim: To evaluate the value of abdominal ultrasonography (US) in the follow-up of paediatric patients with ulcerative colitis (UC) compared to faecal calprotectin (FC) and colonoscopy. Material and method: In this retrospective study we enrolled 30 paediatric patients previously diagnosed with UC, examined by abdominal US and colonoscopy within the same week. FC was also determined during the same week. Disease activity was established using the paediatric ulcerative colitis activity index (PUCAI). The global endoscopic activity was evaluated using the Mayo endoscopic subscore. Results: Endos-copy revealed pathological findings of active disease in 27 out of 30 patients; 3 patients were in endoscopic remission. Only 18 of them had clinical active disease (PUCAI >10), [sensitivity (Se) 66.7% and specificity (Sp) 33% of PUCAI in detecting endoscopic active disease). Twenty-three (76.7%) patients had FC >250 mcg/g, but in 2 of these cases the colonoscopy was normal (Se 77.8% and Sp 33.3% in detecting active disease). At US examination, pathological findings (increased bowel wall thickness, hypervascularity, lymphadenopathies, and/or mesenteric inflammatory fat) were found in 27 patients (90%), all with endoscopic active disease (agreement US - colonoscopy, at patient level, k=1.0, p<0.001, Se 100% and Sp 100%). At seg-ment level (totally 180 bowel segments examined by US), the overall agreement between US and colonoscopy was k=0.767, p<0.001, Se 86.5%, Sp 90.1%. Of the 27 patients with US pathological findings in any of colonic segments, 23 had FC >250 mcg/g (85.1%). The inter-observer agreement for the US measurements had an overall ICC of 0.926 with p<0.001. Conclusion: Abdominal US findings demonstrate a good to excellent concordance with endoscopic examination and are correlated with elevated FC levels. Therefore, US appears as an accurate technique in assessing activity in patients with UC and might replace colonoscopic evaluation for the follow-up.

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