Paclitaxel-eluting balloon angioplasty and cobalt-chromium stents versus conventional angioplasty and paclitaxel-eluting stents in the treatment of native coronary artery stenoses in patients with diabetes mellitus

Abstract

The clinical and angiographic outcome of the combination of the drug-eluting balloon SeQuent Please with a cobalt chromium stent compared to the drug eluting Taxus stent are similar.

Drug-eluting balloons with provisional bail-out or adjunctive stenting in de novo coronary artery lesions—a systematic review and meta-analysis

“…Studies recruited from different patient populations. In the trial by Ali and colleagues (31), all patients were diabetic; whereas, in trials conducted by Besic et al (23) and Poerner et al (25) all patients were hypertensive. Data for each trial are detailed in Table 2.…”

“…Following screening for replicates, 405 remained; and after screening abstracts for relevance, a further 371 studies were removed. Finally, full text of the remaining 34 studies were screened, of which 17 randomised controlled trials (17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34) fulfilled the inclusion criteria and were qualitatively and quantitatively analysed.…”

Time course of vascular response after an a priori strategy of bare metal stent implantation post-dilated with a paclitaxel-coated balloon: Implementation of a three-dimensional analysis algorithm with optical coherence tomography

“…Previous studies have shown inconsistent results regarding the antiproliferative strength of such an adjunctive procedure [5][6][7][8][9][10]. Yet, no data about the time course of arterial vessel response and stent coverage after such a procedure is available.…”

Stent Coverage and Neointimal Proliferation in Bare Metal Stents Postdilated With a Paclitaxel-Eluting Balloon Versus Everolimus-Eluting Stents

“…Thus, we cannot anticipate whether the greater, but diffuse proliferation in the DEB stent group possibly translate into a relevant in-stent restenoses at a later stage. In a study from Ali et al, 11 comparing DEB+BMS versus DEB, significant differences for binary restenosis, major adverse cardiovascular events, or revascularization procedures after 9 months were also not observed. Previously reported data of neointimal proliferation after a DEB stent procedure is similar to ours (relative proliferation volume: 26.1% in this trial versus 25.1% in Gutiérrez-Chico et al).…”

“…[5][6][7][8][9] To date, there is limited knowledge on the combination of bare metal stent (BMS) postdilated with a drug-eluting balloon. [10][11][12] Optical coherence tomography (OCT) is a new gold standard in intravascular imaging allowing the assessment of detailed vessel and stent structures with an axial resolution of 10 to 20 μm. Evolved algorithms to evaluate 2-and 3-dimensional proliferation parameters with OCT are of crucial importance to gain additional benefit compared with standard quantitative coronary angiography but are often deficient in reported OCT studies.…”