Pacific oyster mortality syndrome: a marine herpesvirus active in Australia

Whittington, Richard J.; Hick, Paul; Evans, Olivia; Rubio, Ana; Dhand, Navneet K.; Paul-Pont, Ika

doi:10.1071/ma16043

Cited by 7 publications

(5 citation statements)

References 20 publications

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“…Irrespective of their unsolved origin and partially uncharacterized phylogenetic relationships with other viruses, Malacoherpesviruses represent an authentic concern for aquaculture 17,26,34–38 . In particular, HaHV-1 greatly challenged the abalone production in China as well as in other regions 4,12 .…”

Section: Discussionmentioning

confidence: 99%

RNA-seq of HaHV-1-infected abalones reveals a common transcriptional signature of Malacoherpesviruses

Bai

Rosani

et al. 2019

Sci Rep

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Haliotid herpesvirus-1 (HaHV-1) is the viral agent causative of abalone viral ganglioneuritis, a disease that has severely affected gastropod aquaculture. Although limited, the sequence similarity between HaHV-1 and Ostreid herpesvirus-1 supported the assignment of both viruses to Malacoherpesviridae, a Herpesvirales family distantly related with other viruses. In this study, we reported the first transcriptional data of HaHV-1, obtained from an experimental infection of Haliotis diversicolor supertexta. We also sequenced the genome draft of the Chinese HaHV-1 variant isolated in 2003 (HaHV-1-CN2003) by PacBio technology. Analysis of 13 million reads obtained from 3 RNA samples at 60 hours post injection (hpi) allowed the prediction of 51 new ORFs for a total of 117 viral genes and the identification of 207 variations from the reference genome, consisting in 135 Single Nucleotide Polymorphisms (SNPs) and 72 Insertions or Deletions (InDels). The pairing of genomic and transcriptomic data supported the identification of 60 additional SNPs, representing viral transcriptional variability and preferentially grouped in hotspots. The expression analysis of HaHV-1 ORFs revealed one putative secreted protein, two putative capsid proteins and a possible viral capsid protease as the most expressed genes and demonstrated highly synchronized viral expression patterns of the 3 infected animals at 60 hpi. Quantitative reverse transcription data of 37 viral genes supported the burst of viral transcription at 30 and 60 hpi during the 72 hours of the infection experiment, and allowed the distinction between early and late viral genes.

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Section: Discussionmentioning

confidence: 99%

RNA-seq of HaHV-1-infected abalones reveals a common transcriptional signature of Malacoherpesviruses

Bai

Rosani

et al. 2019

Sci Rep

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“…High mortalities associated with OsHV-1 µVar were observed in Swedish and Norwegian hatcheries towards the end of 2014 (Mortensen et al 2016). More recently, a new outbreak in Tasmania in 2016 has crippled the Australian oyster aquaculture sector and its selective breeding program (Davis 2016;Milne 2016;Whittington et al 2016). Thus, it is clear that the extent of this new variant's geographical reach is indeed a major global concern.…”

Section: Introductionmentioning

confidence: 99%

Differential expression of novel metabolic and immunological biomarkers in oysters challenged with a virulent strain of OsHV-1

Young

Kesarcodi-Watson

Alfaro

et al. 2017

Developmental & Comparative Immunology

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Villas-Bôas, S., Differential expression of novel metabolic and immunological biomarkers in oysters challenged with a virulent strain of OsHV-1, Developmental and Comparative Immunology (2017), doi: 10.1016/j.dci.2017 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. and immunological responses in oyster larvae exposed to OsHV-1 µVar; some of which have 34 not previously been reported in molluscs. Multivariate analyses of entire metabolite profiles 35 were able to separate infected from non-infected larvae. Correlation analysis revealed the 36 presence of major perturbations in the underlying biochemical networks and secondary 37 pathway analysis of functionally-related metabolites identified a number of prospective 38 pathways differentially regulated in virus-exposed larvae. These results provide new insights 39 into the pathogenic mechanisms of OsHV-1 infection in oyster larvae, which may be applied 40 to develop disease mitigation strategies and/or as new phenotypic information for selective 41 breeding programmes aiming to enhance viral resistance. 42

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“…This included a new local legislative requirement, SEPP62, for all developments that could have estuarine impacts [104,127] 2 Such proactive collaborative engagement, supported by best available information, has led to the NSW Oyster industry being seen by many catchment, government and community leaders as 'stewards' of the estuary and their oysters as the 'canaries of the catchment' [106], providing early warning on catchment, estuary and marine environment health [72]. However, the 2014 OsHV-1 oyster disease outbreak in the Lower Hawkesbury estuary, has demonstrated continuing fragility and vulnerability of the oyster aquaculture industry, despite the oyster farmers' capacity to self-organise and take a key role in collective estuarine governance [107,108].…”

Section: Discussion Theme 3: Risks and Their Governancementioning

confidence: 99%

Evolutions in estuary governance? Reflections and lessons from Australia, France and New Caledonia

et al. 2020

Self Cite

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Estuaries are cradles of life for the communities who live around and within them. They are valued in multiple ways for the services they provide to humans, including food production, recreation, water purification, navigation and amenity. Various groups of stakeholders all place different importance on these values, how their needs and practices interact, and what it means to effectively manage an estuary towards a range of desirable goals. This typically creates value conflicts over how estuaries should be managed. Navigating such conflicts requires governance arrangements and methods that allow multiple parties to find a common path forward. Using Evolutionary Governance Theory (EGT) and a hybrid analytic framework incorporating aspects of multilevel/multi-scalar governance, risk governance and territorial intelligence theory, this paper explores the (co-) evolution of governance processes by analysing lessons learnt from action in and observation of estuaries in Australia (Lower Hawkesbury), France (Thau) and New Caledonia (Thio). A multi-method research approach to data collection was used and comparative analysis across the three estuaries undertaken to understand the evolutions in each of their governance systems. From this analysis, several reflections and lessons for the governance of other land-sea systems emerge on: the importance of boundary organisations and boundary negotiations in re-defining integrated approaches to land-sea governance; how particular information systems or models, as well as discourses from other key actors shape co-evolutions of estuarine governance; and that risks or shocks still appear to be the catalysers of new forms of collective action and major reconfigurations and evolutions of estuarine governance.

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Pacific oyster mortality syndrome: a marine herpesvirus active in Australia

Abstract: Want to upgrade from an associate to a full member?No points or cash required and only one supporting referee needed.Go to the ASM website, download and complete the form, and forward it with a CV to the National Office.We will do the rest.Under the Microscope

Cited by 7 publications

References 20 publications

RNA-seq of HaHV-1-infected abalones reveals a common transcriptional signature of Malacoherpesviruses

RNA-seq of HaHV-1-infected abalones reveals a common transcriptional signature of Malacoherpesviruses

Differential expression of novel metabolic and immunological biomarkers in oysters challenged with a virulent strain of OsHV-1

Evolutions in estuary governance? Reflections and lessons from Australia, France and New Caledonia

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