Pachypophyllin and pachypostaudins A and B: three bisnorlignans from pachypodanthium staudtii☆

Synthesis of cyclobutane lignans via an organic single electron oxidant–electron relay system

“…According to Bamya and coworkers, the structure of the head-to-head dimer was proposed to be the meso isomer. 8 To verify the stereochemistry, X-ray quality crystals were obtained, which unambiguously revealed the trans geometry of the cyclobutane substituents. Lastly, the dimerization of N -vinyl carbazole, which had been previously reported by Bauld, furnished the desired cycloadduct in a quantitative yield (entry 4).…”

“…5 Despite the biological importance of this class of compounds, there have been few efforts devoted to the stereoselective synthesis of cyclobutane lignans and potentially valuable analogs. Herein, we report a method for the stereoselective synthesis of C 2 -symmetric cyclobutane alkene dimers (eqn (1)) that has been applied to the total syntheses of the lignans magnosalin, 6 endiandrin A, 3,7 and the lignan-like cyclobutane, pellucidin A, 8 of which we propose a revised structure. …”

Synthesis and Hypolipidemic Activity of Modified Side Chain α-Asarone Homologues

“…However, the HDL cholesterol concentration level was exceeded considerably for the former. Compound 10a has been, on the other hand, isolated from Piperaceae and Annonaceae families [26,28], and it shows cytotoxic activity [29].…”

Isolation and Characterization of 2,4,5-Trimethoxy-benzaldehyde and 1-(2,4,5-trimethoxyphenyl)-Ethanone from Pachypodanthium Staudtii, and their General Toxicity towards Brine Shrimps

“…Pachypodanthium staudtii Engl. & Diels (Family: Annonaceae) is native to the tropical forest zone of West and Central Africa [1]. A bark decoction from this plant has been used traditionally for killing headlice [2].…”