Pachychoroid Neovasculopathy

Abstract

Pachychoroid neovasculopathy falls within a spectrum of diseases associated with choroidal thickening that includes pachychoroid pigment epitheliopathy, central serous chorioretinopathy, and polypoidal choroidal vasculopathy and should be considered as a possible diagnosis in eyes with features of Type 1 neovascularization and choroidal thickening in the absence of characteristic age-related macular degeneration or degenerative changes. Pachychoroid neovasculopathy may occur as a focal abnormality within the macula, even in myopic eyes with normal subfoveal choroidal thickness. Pachychoroid neovasculopathy can ultimately progress to the development of polypoidal choroidal vasculopathy.

Pachychoroid neovasculopathy in a male patient: a case report

“…PN was originally reported in three white female patients (1) . In this report, we describe a case of PN in a male patient.…”

“…Thus, PN does not appear to be gender-specific and may occur in white male populations. The original paper (1) reported a mean subfoveal choroidal thickness in affected eyes of 310 µm with a range of 244 µm-407 µm. In our case study, a subfoveal choroidal thickness of 247 µm was recorded in the affected eye; thus, our results corroborate the EDI-OCT findings of the original report (1) .…”

“…The original paper (1) reported a mean subfoveal choroidal thickness in affected eyes of 310 µm with a range of 244 µm-407 µm. In our case study, a subfoveal choroidal thickness of 247 µm was recorded in the affected eye; thus, our results corroborate the EDI-OCT findings of the original report (1) . In the original paper, polypoidal vascular lesions were observed in two of the three patients but were not observed in the patient described in this report at any point during diagnosis or treatment.…”

“…The term pachychoroid neovasculopathy (PN) was first coined by Freund (1) to describe a disease characterized by a form of type 1 (subretinal pigment epithelium) neovascularization involving dilated choroidal vessels in areas of increased choroidal thickness. Recently, it was posited that PN (1) should be grouped with macular diseases, including central serous chorioretinopathy (2) and pachychoroid pigment epitheliopathy (3) , in which choroidal thickening of the macular region is demonstrated by enhanced depth imaging (EDI)-optical coherence tomography (OCT).…”

“…Recently, it was posited that PN (1) should be grouped with macular diseases, including central serous chorioretinopathy (2) and pachychoroid pigment epitheliopathy (3) , in which choroidal thickening of the macular region is demonstrated by enhanced depth imaging (EDI)-optical coherence tomography (OCT). In the first published paper regarding PN, Pang and Freund (1) described the occurrence of PN in three white female patients. Herein, we report the case of a male patient diagnosed with PN and provide descriptions of our subsequent multimodal evaluation of this patient.…”