Pacemaker Interactions with Transcutaneous Cardiac Pacing

Kemnitz, Jürgen

doi:10.1097/00000542-199308000-00028

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“…Im Notfall läßt sich bei einem VVISchrittmacher durch eine Brustwandstimulation eine Inhibition erzielen. In diesem Fall nimmt der Schrittmacher das durch die Brustwandstimulation (zum Beispiel Alpha ITX ® ) aufgebaute elektrische Feld wahr und wird dann dadurch inhibiert, daß die eingestellte Frequenz des externen Schrittmachers über der des permanenten Gerätes liegt [1,[5][6]. Bei einem DDD-Schrittmacher ist die Brustwandstimulation ineffektiv, weil sie eine atriale Triggerung bewirkt.…”

Section: Repeated Ventricular Fibrillation After Defibrillation In a unclassified

Rezidivierendes Kammerflimmern nach Defibrillation bei einem Schrittmacherpatienten

Wilke¹,

Noll²,

Maisch

2000

Med Klin

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Section: Repeated Ventricular Fibrillation After Defibrillation In a unclassified

Rezidivierendes Kammerflimmern nach Defibrillation bei einem Schrittmacherpatienten

Wilke¹,

Noll²,

Maisch

2000

Med Klin

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Passagere Schrittmachertherapie

Heinroth

Werdan

2000

Der Internist

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Mechanism of the negative inotropic effect of midazolam and diazepam in cultured foetal mouse cardiac myocytes

Nonaka¹,

Kashimoto²,

Imamura³

et al. 1997

Eur J Anaesthesiol

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We have investigated the effects of midazolam and diazepam on intracellular calcium (Ca2+) handling in foetal mouse ventricular myocytes using the Ca(2+)-sensitive fluorescent indicator, indo-1. We also investigated separately whether flumazenil or the L-type Ca2+ channel agonist, Bay K8644, antagonized these myocardial depressive effects. Midazolam and diazepam decreased the Ca2+ transient and beating rate in a concentration-dependent manner, and these decreases were prevented by Bay K8644. Flumazenil did not antagonize the myocardial depressive effects. In myocytes whose sarcoplasmic reticulum was inhibited by ryanodine, midazolam and diazepam had the same potent cardiodepressive effects. Midazolam and diazepam are direct cardiac depressants, which decrease the Ca2+ transient and beating rate, and the L-type Ca2+ channel is important in the negative inotropism and chronotropism caused by these drugs.

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Pacemaker Interactions with Transcutaneous Cardiac Pacing

Cited by 5 publications

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Rezidivierendes Kammerflimmern nach Defibrillation bei einem Schrittmacherpatienten

Rezidivierendes Kammerflimmern nach Defibrillation bei einem Schrittmacherpatienten

Passagere Schrittmachertherapie

Mechanism of the negative inotropic effect of midazolam and diazepam in cultured foetal mouse cardiac myocytes

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