P958 Effect of breast feeding on pain relief during immunization injection

Pharmacological and Combined Interventions to Reduce Vaccine Injection Pain in Children and Adults

“…The analgesic effect of breastfeeding was examined in 9 trials 22 – 27 , 29 , 30 , 33 including data on 858 infants (0 to 12 mo). In all studies, breastfeeding was commenced immediately before vaccination and continued during and afterward.…”

“…In the included trials, the comparator arm varied from the infant being swaddled in the bassinet/placed on the table 24 , 26 held in the mother’s arms, 27 , 29 restrained by the mother, 22 given distilled water 25 to a no intervention roup. 23 , 30 , 33…”

“…The SMD was −1.78 (CI, −2.35, −1.22) for acute distress (n=792; data from 8 studies). 22 , 23 , 25 – 27 , 29 , 30 , 33 For distress during the acute plus recovery phase (n=424) the SMD was −1.89 (CI, −3.19, −0.59). Considerable heterogeneity was reported for this outcome, which can be explained by the potential differences in the implementation of the intervention (breastfeeding and the control group) and age of the infant (studies included infants less than 24 h of age to up to 12 mo).…”

Procedural and Physical Interventions for Vaccine Injections

“… 3 Thirty-seven studies investigating procedural and physical interventions were included in the review. 10 – 46 In 6 cases, multiple citations were identified for the same study; 3 of them included a dissertation 41 – 43 and published manuscript of the same data, 20 , 30 , 33 and the other 3 included multiple citations 44 – 46 to the same study. 27 The profile summarizing the trial flow is shown in Figure 1 .…”

Comparison of two different methods of reducing pain during vaccination in infants: A clinical study

“…Understandably, the implementation of vaccination programme and ensuring that the benefits of vaccines reach to each and every possible beneficiary is a challenging task [4] . Some effective non-medical methods to manage pain include cryotherapy, acupressure, distraction, and music therapy [5] . Medical methods are rarely used in infancy due to their side effects like skin rashes and irritations, while non-medical pain relief methods have not only numerous advantages including lack of side effects and interference with vaccination, but a pleasant effect on infants as well.…”