P792Smoking is the dominating modifiable risk factor in younger patients with STEMI

Gleerup, H; Dahm, Christina Catherine; Thim, Troels; Jensen, Svend Eggert; Jensen, Lisette Okkels; Kristensen, Steen Dalby; Boetker, H.E.; Mæng, Michael

doi:10.1093/eurheartj/ehy564.p792

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“…[1][2][3] Cigarette smoking, a common risk factor accountable for the development of coronary heart disease, was found in as high as 74% of STEMI patients aged 30 -49, compared to only about 30% in older patients aged > 70. 5 Young STEMI patients also have a higher chance to have a JMR 148 E9 ( 12) -2021 follow-up period, there was no remarkable difference in repeated PCI or re-infarction but overall mortality is significantly lower in young patients compared to their older counterparts. 1 Our patient recovered well from the infarction, which was consistent with the literature on young STEMI cases.…”

Section: Discussionmentioning

confidence: 93%

ST-elevation myocardial infarction complicated by cardiac arrest in a young patient with familiar dyslipidemia

Tuấn¹,

Vu²

2021

TCNCYH

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Coronary heart disease in young patients always poses great challenges for every healthcare system with differences in clinical manifestations, etiology, epidemiology, angiographic characteristics and prognosis. The objective of this study was to describe a case of ST-elevation myocardial infarction complicated by cardiac arrest in a young patient with familial dyslipidemia. A 30-year-old male visited our hospital with typical angina. During the examination, he suﬀered a sudden loss of consciousness, the monitor showed ventricular fibrillation. After successful resuscitation of cardiac arrest, electrocardiography showed apparent ST-elevation from V2 to V6 leads consistent with the diagnosis of anterolateral infarction. Emergency coronary angiogram showed severe three-vessel lesions including complete occlusion of the LAD artery and 80 - 90% stenosis of the other two coronary branches. Our patient’s coronary arteries were revascularized using drug-eluting stents in LAD artery and subsequently RCA artery, stem cell therapy was applied during the interventional process. Routine laboratory test results showed dyslipidemia and his family records suggested familiar (hereditary) dyslipidemia which affected his mother and sister. 1-month follow-up echocardiography showed a drastic improvement of LVEF by roughly 15%. The combination of revascularization, stem cell therapy, and lipid-lowering therapy has shown a good therapeutic effect.

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