P773 Sarcopenia is a new risk factor of non-alcoholic fatty liver disease in patients with inflammatory bowel disease

Jang, Byung Ik; Kim, K O; Ch, Yang

doi:10.1093/ecco-jcc/jjy222.897

Cited by 1 publication

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“…An interesting recent study including 488 IBD patients assessed the study population for NAFLD, defined on the basis of a CT-scan, and sarcopenia. NAFLD was present in 11.1% of the study population and the prevalence of sarcopenia was 34.9%, suggesting that it was an independent risk factor for NAFLD after taking age, sex and metabolic factors into consideration [ 49 ].…”

Section: Nafld Warning In Underweight and Lean Patientsmentioning

confidence: 99%

The Other Side of Malnutrition in Inflammatory Bowel Disease (IBD): Non-Alcoholic Fatty Liver Disease

et al. 2021

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Steatohepatitis and hepatobiliary manifestations constitute some of the most common extra-intestinal manifestations of Inflammatory Bowel Disease (IBD). On the other hand, non-alcoholic fatty liver disease (NAFLD) affects around 25% of the world’s population and is attracting ever more attention in liver transplant programs. To outline the specific pathways linking these two conditions is a pressing task for 21st-century researchers. We are accustomed to expecting the occurrence of fatty liver disease in obese people, but current evidence suggests that there are several different pathways also occurring in underweight patients. Genetic factors, inflammatory signals and microbiota are key players that could help in understanding the entire pathogenesis of NAFLD, with the aim of defining the multiple expressions of malnutrition. In the current review, we summarize the most recent literature regarding the epidemiology, pathogenesis and future directions for the management of NAFLD in patients affected by IBD.

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Section: Nafld Warning In Underweight and Lean Patientsmentioning

confidence: 99%